Furacilin Reneval, tablets 20 mg 20 pcs

Pharmacodynamics

Antimicrobial agent, nitrofuran derivative. Bacterial flavoproteins, by reducing 5-nitro group, form highly reactive amino derivatives that can cause conformational changes in proteins (including ribosomal) and other macromolecules, leading to the death of bacteria. Active against Gram-positive and Gram-negative bacteria (including Staphylococcus spp., Streptococcus spp., Escherichia coli, Clostridium perfringens). Resistance develops slowly and does not reach a high degree.

Pharmacokinetics

In external and topical application absorption is insignificant. It penetrates through histohematic barriers and is evenly distributed in fluids and tissues. The main route of metabolism is reduction of the nitro group. It is excreted by the kidneys and partially with bile.

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