Furacilin Reneval, tablets 20 mg 10 pcs

Pharmacodynamics

Antimicrobial agent, nitrofuran derivative. Bacterial flavoproteins, by reducing 5-nitro group, form highly reactive amino derivatives that can cause conformational changes in proteins (including ribosomal) and other macromolecules, leading to the death of bacteria. Active against Gram-positive and Gram-negative bacteria (including Staphylococcus spp., Streptococcus spp., Escherichia coli, Clostridium perfringens). Resistance develops slowly and does not reach a high degree.

Pharmacokinetics

In external and topical application absorption is insignificant. It penetrates through histohematic barriers and is evenly distributed in fluids and tissues. The main route of metabolism is reduction of the nitro group. It is excreted by the kidneys and partially with bile.

Indications

Externally: purulent wounds, bedsores, II-III degree burns, minor skin damage (including abrasions, scratches, cracks, cuts).
Locally: blepharitis, conjunctivitis, osteomyelitis, empyema of the paranasal sinuses and pleura; urinary tract infections – lavage of cavities, acute tonsillitis, stomatitis, gingivitis.
If necessary, please consult your doctor before using the medicine.

Pharmacological effect

Pharmacodynamics

Antimicrobial agent, nitrofuran derivative. Bacterial flavoproteins, by reducing the 5-nitro group, form highly reactive amino derivatives that can cause conformational changes in proteins (including ribosomal ones) and other macromolecules, leading to the death of bacteria. Active against gram-positive and gram-negative bacteria (including Staphylococcus spp., Streptococcus spp., Escherichia coli, Clostridium perfringens). Resistance develops slowly and does not reach a high degree.

Pharmacokinetics

When applied externally and locally, absorption is negligible. Penetrates through histohematic barriers and is evenly distributed in liquids and tissues. The main route of metabolism is the reduction of the nitro group. Excreted by the kidneys and partially with bile.

Active ingredient

Nitrofural

Composition

Composition per tablet
Active ingredient:
Nitrofural (furacilin) ​​– 20 mg
Excipient:
sodium chloride – 800 mg

Pregnancy

Before using the drug, if you are pregnant, or think you might be pregnant, or are planning a pregnancy, you should consult your doctor while breastfeeding.
Use during pregnancy and breastfeeding is possible if the expected benefit to the mother outweighs the potential risk to the fetus or child.

Contraindications

Hypersensitivity to nitrofural, nitrofuran derivatives and/or other components of the drug, bleeding, allergic dermatoses, severe renal dysfunction.

Side Effects

Allergic reactions, dermatitis, itching are possible. If any of the side effects indicated in the instructions worsen, or any other side effects not listed in the instructions are noted, you should immediately inform your doctor.

Interaction

Not studied.

Shelf life

5 years.

Manufacturer

Update of PFC JSC, Russia