Famotidine, 20 mg 30 pcs

Famotidine has an antiulcer effect. Blocker of H2-histamine receptors of III generation. Suppresses basal and stimulated by histamine, gastrin and acetylcholine production of hydrochloric acid. Reduces the activity of pepsin.

It enhances the protective mechanisms of the gastric mucosa, promotes healing of lesions associated with the impact of hydrochloric acid (including scarring of stress ulcers) and cessation of gastrointestinal bleeding by increasing the formation of gastric mucus, its glycoprotein content, stimulation of secretion of hydrocarbonate by the gastric mucosa, endogenous synthesis of prostaglandins in it and the rate of regeneration. It does not significantly change the level of gastrin in plasma.

It weakly inhibits cytochrome P450 oxidase system in the liver.

After oral administration the action begins after 1 hour, reaches a maximum within 3 hours. The duration of action of the drug in a single dose depends on the dose and varies from 12 to 24 hours.

Indications

Active ingredient

Composition

1 tablet contains:

The active ingredient:

Famotidine 20 mg;

Associates:

Corn starch,

Microcrystalline cellulose,

Silicon dioxide,

How to take, the dosage

Orally, swallowed whole (without chewing), with plenty of water. In gastric ulcer and duodenal ulcer in acute phase, symptomatic ulcers, erosive gastroduodenitis – usually 20 mg twice daily or 40 mg once daily at bedtime. If necessary, daily dose may be increased to 80-160 mg. The course of treatment is 4-8 weeks.

In case of dyspepsia associated with increased secretory function of the stomach, 20 mg 1-2 times a day.

In order to prevent recurrence of peptic ulcer disease – 20 mg once a day before going to bed.

In reflux esophagitis – 20-40 mg 2 times a day for 6-12 weeks.

In Zollinger-Ellison syndrome the dose of the drug and the duration of treatment are determined individually. The initial dose is usually 20 mg every 6 hours and may be increased to 160 mg every 6 hours.

To prevent aspiration of gastric juice during general anesthesia, 40 mg in the evening and/or in the morning before surgery.

In case of renal insufficiency (at Cl creatinine3 mg/100 ml) the daily dose of the drug should be reduced to 20 mg.

Interaction

Antacids interfere with absorption (a break of at least 1-2 hours between intake of antacids and famotidine is recommended).

Special Instructions

Before treatment, it is necessary to rule out the presence of a malignant process in the gastrointestinal tract.

Contraindications

Hypersensitivity, pregnancy, lactation.

Side effects

Rarely, headache, dizziness, fatigue, dry mouth, lack of appetite, diarrhea or constipation, skin rash.

Similarities