Exiter, cream 1% 15 g

Antifungal drug for external use with a broad spectrum of antifungal activity. In low concentrations terbinafine has fungicidal effect against dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton violaceum, Trichophyton tonsurans, Microsporum canis, Epidermophyton floccusom).

Moderately sensitive: molds (mainly Candida albicans) and dimorphic fungi (Pityrosporum orbiculare (also known as Malassezia furfur)). Activity against yeast fungi, depending on their species, can be fungicidal or fungistatic.

Terbinafine specifically alters the early stage of sterol biosynthesis in fungi, by inhibiting the squalene epoxidase enzyme located on the cell membrane of the fungus. This leads to ergosterol deficiency and to intracellular accumulation of squalene, which causes cell death of the fungus.

Terbinafine has no effect on the metabolism of hormones or other drugs.

Pharmacokinetics

On external use, absorption is less than 5% and has little systemic effect.

Indications

Active ingredient

Composition

How to take, the dosage

Interaction

Special Instructions

If you have any questions about the use of this drug, consult your doctor.
The drug is intended for external use only. Avoid getting it on the mucous membranes of the eyes, nose and mouth as it may cause irritation.

In case of accidental contact of the drug in the eyes, they should be immediately rinsed with running water, and if persistent irritation develops, seek medical attention.

If allergic reactions develop, the drug should be discontinued.

In the course of treatment, general rules of hygiene should be followed to prevent reinfection (through underwear, shoes).

In order to increase the effectiveness of treatment, it is recommended to avoid contact with possible external sources of fungal infection.

Ingregular use or stopping treatment prematurely increases the risk of recurrence.

Contraindications

Hypersensitivity to terbinafine, to other components of the drug; childhood (under 12 years), lactation.

Hepatic/liver failure, alcoholism, suppression of bone marrow hematopoiesis, tumors, metabolic diseases, vascular occlusive disease of the extremities.

If you have any of the conditions listed in this section, you should talk to your doctor before starting this medicine.

Side effects

Overdose

Pregnancy use

Similarities