Erythromycin, eye ointment 10000 units/g tube 10 g

Erythromycin is an antibacterial agent of the macrolide group, which is produced by Streptomyces erythreus. The action of the drug is bacteriostatic.

It has antibacterial action against a large number of Gram-positive and Gram-negative microorganisms (different types of N. gonorrhoeae, N. Meningitidis, Streptococcus, Staphylococcus), including strains of bacteria resistant to other antibiotics. Erythromycin is also active against Actinomyces israelii, Mycoplasma pneumoniae, Ciostridium spp., Corynebacterium diphtheriae, Listeria monocytogenes, Haemophilus influenzae, chlamydia.

Most gram-negative bacteria, viruses, mycobacteria and fungi are resistant to the drug.

Eritromycin tolerance is better than that of the penicillins, so it can be prescribed if there is an allergy to the latter. Microflora develop resistance to erythromycin quickly.

Indications

Active ingredient

Composition

1 g eye ointment contains:

Active substance:

erythromycin (in terms of the active substance) – 10000 IU

Ancillary components:

Lanolin anhydrous – 0.4 g,

Sodium disulfite – 0.0001 g,

Vaseline special – up to 1 g.

How to take, the dosage

The ointment should be applied behind the lower eyelid three times a day, in the treatment of trachoma up to 5 times a day. The duration of therapy depends on the severity and form of the disease, but it should not exceed 2 weeks.

The treatment of trachoma with erythromycin should be combined with the opening of purulent follicles. When the process of inflammation subsides, the drug is used three times a day. The course of treatment of trachoma should not exceed three months.

Interaction

Erythromycin is an antagonist of lincomycin, clindamycin, chloramphenicol. It can significantly reduce the bactericidal effect of beta-lactam antibacterial agents (penicillins, cephalosporins, carbopenems).

The simultaneous use of medicinal external forms of erythromycin and abrasive substances that cause skin irritation, or with agents that cause skin exfoliation, may cause a cumulative irritating or drying effect.

Special Instructions

The drug is prescribed with caution in patients with liver and/or kidney dysfunction.

Erythromycin may be prescribed in case of allergy to penicillins.

Erythromycin is not recommended with milk and dairy products.
Erythromycin penetrates the placenta and is excreted with breast milk, so when prescribing the drug during pregnancy and lactation, the estimated benefit to the mother and the potential risk to the fetus should be assessed.

In order to prevent neonatal ophthalmia, washing eye ointment out of the eye is not recommended. In children whose mothers have severe gonorrhea, erythromycin is recommended to be used concomitantly with penicillin G (aqueous) solution for parenteral administration.

Contraindications

Side effects

The use of the ointment may have an irritant effect (redness, itching).

Long-term use may lead to secondary infection caused by erythromycin-resistant microorganisms.

Overdose

The data is not described.

Similarities