The spectrum of Ergoferon pharmacological activity includes antiviral, immunomodulatory, antihistamine, anti-inflammatory.
The effectiveness of Ergoferon components for viral infectious diseases has been experimentally and clinically proved: influenza A and influenza B, acute respiratory viral infections (caused by parainfluenza viruses, adenoviruses, respiratory syncytial viruses, coronaviruses), herpesvirus infections (labial herpes, ophthalmoherpes, genital herpes, herpes zoster, Chicken pox, infectious mononucleosis), acute intestinal infections of viral etiology (caused by caliciviruses, coronaviruses, rotaviruses, enteroviruses), enteroviral and meningococcal meningitis, hemorrhagic fever with renal syndrome, encephalitis.
Ergoferon is used in combination therapy of bacterial infections (pseudotuberculosis, whooping cough, yersiniosis, pneumonia of various etiologies including atypical pathogens (M. pneumoniae, C. Pneumoniae, Legionella spp), is used for prevention of bacterial complications of viral infections, prevents the development of superinfections. The usage of Ergoferon during pre- and post-vaccination period increases the effectiveness of vaccination, provides non-specific prophylaxis of ARVI and flu in the period of post-vaccination immunity establishment. Ergoferon possesses prophylactic effectiveness against acute respiratory viral infections of non-flu etiology, prevents the development of intercurrent diseases in postvaccination period.
Components of Ergoferon possess the same mechanism of action as activation of functional activity of CD4 receptor, receptors to interferon gamma (IFN-γ) and histamine, correspondingly accompanied by pronounced immunotropic action.
It was experimentally proved that antibodies to interferon gamma:
increase expression of IFN-γ, IFN α/β and associated interleukins (IL-2, IL-4, IL-10 and others).), improve ligand-receptor interaction of IFN, restore cytokine status; normalize the concentration and functional activity of natural antibodies to IFN-γ, which is an important factor in the natural antiviral tolerance of the body; stimulate interferon-dependent biological processes: induction of expression of antigens of the main histocompatibility complex of types I, II and Fc-receptors, monocyte activation, stimulation of functional activity of NK-cells, regulation of immunoglobulin synthesis, activating mixed Th1 and Th2 immune response.
Antibodies to CD4, being probably allosteric modulators of the receptor, regulate functional activity of CD4 receptor that results in increase of functional activity of CD4 lymphocytes, normalization of immunoregulatory index CD4/CD8 as well as subpopulation structure of immunocompetent cells (CD3, CD4, CD8, CD16, CD20).
. Antibodies to histamine modify histamine-dependent activation of peripheral and central H1-receptors, thus reducing tone of bronchial smooth muscle and capillary permeability that results in reduction of duration and severity of rhinorrhea, nasal mucous membrane edema, cough and sneezing,
Allergic reactions accompanying infectious process decrease due to suppression of histamine release from mast cells and basophils, leukotrienes production, adhesion molecules synthesis, decrease of eosinophils chemotaxis and platelet aggregation in reactions to contact with allergen.
Combined use of components of Ergoferon complex preparation is accompanied by enhanced antiviral activity of its components.
Indications
Active ingredient
Composition
How to take, the dosage
Interaction
Incompatibilities with other medications have not been reported to date.
Special Instructions
Synopsis
Contraindications
Side effects
Overdose
In an accidental overdose, dyspepsia is possible due to the excipients in the drug.
Pregnancy use
Similarities
Weight | 0.016 kg |
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Shelf life | 3 years. Do not use after the expiration date. |
Conditions of storage | In the dark place at a temperature not exceeding 25 ° C. Keep out of reach of children. |
Manufacturer | Materiala Medica Holding, Russia |
Medication form | lozenges |
Brand | Materiala Medica Holding |
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