Elcar, 300 mg/ml 50 ml

Elcar is a remedy for the correction of metabolic processes.

L-carnitine (a natural substance related to the B vitamins) is involved in metabolic processes as a carrier of fatty acids through cell membranes from the cytoplasm to the mitochondria where these acids are oxidized (beta-oxidation process) with the formation of large amounts of metabolic energy (in the form of ATP). L-carnitine increases resistance of nervous tissue to damaging factors (hypoxia, injury, intoxication, etc.), inhibits the formation of keto acids and anaerobic glycolysis, reduces lactacidosis.

The drug replenishes alkaline blood reserve, restores autoregulation of cerebral hemodynamics and increases blood supply to the affected area, accelerates reparative processes in the lesion and has an anabolic effect.

Pharmacokinetics

It is well absorbed in the intestine, the concentration in plasma reaches a maximum of 3 hours and remains in therapeutic range for 9 hours. It penetrates easily into the liver and myocardium, slower in the muscles. It is excreted by the kidneys, mainly in the form of acyl esters.

Indications

Headache, Low performance, Eczema

The drug is used as part of complex therapy.

• intensive physical activity and psycho-emotional stress: to improve performance, endurance, reduce fatigue, including in the elderly;
• in rehabilitation after diseases and surgical interventions, injuries, including to accelerate tissue regeneration;
• complex therapy of chronic gastritis and chronic pancreatitis with decreased secretory function;
• complex therapy of skin diseases (psoriasis, seborrheic eczema, focal scleroderma and discoid lupus);
• hyperthyroidism of mild degree;
• neurological manifestations in vascular, toxic, and traumatic brain lesions;
• syndrome of anorexia nervosa;
• in pediatric practice (treatment of children under 3 years old under medical supervision): during nursing of premature infants, newborns after birth trauma or asphyxia; children with sluggish sucking reflex and low weight gain; with reduced muscle tone, insufficient development of motor and mental functions, as well as for the prevention of these disorders in children “at risk”; with growth retardation and weight shortage in children and teenagers under 16.

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Active ingredient

Levocarnitine

Composition

1 ml of oral solution contains:

the active ingredient:

levocarnitine (carniphite) 300 mg;

auxiliary substances:

citric acid monohydrate 1.2 mg,

methyl parahydroxybenzoate 0.5 mg,

propylparahydroxybenzoate 0.2 mg,

purified water up to 1 ml.

How to take, the dosage

1. The drug is used as part of complex therapy. Orally 30 minutes before a meal, additionally diluted with liquid.

In case of prolonged physical and psycho-emotional strain: from 0.75 g (1/2 scoop or 2.5 ml) 3 times a day to 2.25 g (1.5 scoop or 7.5 ml) 2-3 times a day.

In case of anorexia nervosa, as well as during rehabilitation after diseases and surgical interventions and injuries: 1.5 g (1 scoop or 5 ml) 2 times a day. The course of treatment is 1-2 months.

In the complex therapy of chronic gastritis and chronic pancreatitis with decreased secretory function: 0.375 g (1/4 scoop or 1.25 ml) 2 times a day. The course of treatment is 1-1.5 months.

To treat skin diseases: 0.75 g (1/2 scoop or 2.5 ml). The course of treatment is for 2-4 weeks.

In mild hyperthyroidism: 0.25 g (13 drops) 2-3 times a day. The course of treatment is 20 days. The course of treatment is repeated after 1-2 months break or it is prescribed for 3 months without a break.

In case of vascular, toxic and traumatic brain damage: 0.75 g (1/2 scoop or 2.5 ml) a day. The course of treatment is 3-5 days. If necessary the second course is prescribed in 12-14 days.

In children it is prescribed as an additive to sweet dishes (kissel, compote, juices).

In children under 3 years of age the dose is determined by the attending physician. From 3 to 6 years old – a single dose of 0.1 g (5 drops) 2-3 times a day, a daily dose of 0.2-0.3 g (11-16 drops). The course of treatment is 1 month. Children 6 to 12 years of age are prescribed a single dose of 0.2-0.3 g (11-16 drops) 2-3 times a day, a daily dose of 0.4-0.9 g (22-48 drops). The course of treatment is at least 1 month.

In case of growth retardation: 0.25 g (13 drops) 2-3 times a day. The course of treatment is 20 days. The course of treatment is repeated after 1-2 months break or administered for 3 months without a break.

In sports medicine and intensive training: 2.5 g 1-3 times a day (daily dose of 2.5-7.5 g); if used for therapeutic purposes – 70-100 mg/kg/day (5-7.5 g/day). The course of treatment: 3-4 weeks in the pre-competition period. During the training process up to 6-8 weeks.

2. 0,5 g of the active substance is contained in one ampoule.

Elcar is administered intravenously by slow drip or trickle (2-3 min) or intravenously. Before intravenous administration the content of the ampoule is dissolved in 100-200 ml of solvent (0.9% sodium chloride solution or 5% dextrose (glucose) solution).

In acute disorders of cerebral circulation 1 g/day (2 ampoules) is prescribed for 3 days, and then 0.5 g/day (1 ampoule) for 7 days. After 10-12 days repeated courses of 3-5 days are possible.

When the drug is prescribed in the subacute and recovery period, in discirculatory encephalopathy and various brain lesions, carnitine deficiency patients are given Elcar solution at a rate of 0.5-1 g/day (1-2 ampoules) intravenously (drop or stream) or intravenously (2-3 times a day) without dilution for 3-7 days. If necessary, a repeated course is prescribed after 12-14 days.

Interaction

Glucocorticosteroids promote accumulation of the drug in tissues (except the liver), other anabolics enhance the effect.

Special Instructions

Treatment of children under the age of 3 years should be under the supervision of a doctor.

The drug does not affect the performance of potentially hazardous activities requiring particular attention and quick reactions (driving a car and other vehicles, working with moving machinery, work of dispatcher and operator, etc.)

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Contraindications

Individual intolerance to the ingredients of the drug.

Side effects

Allergic reactions, gastralgia, dyspepsia, myasthenia (in patients with uremia) are possible.

Overdose

Symptoms: dyspeptic disorders, myasthenic disorders (in patients with uremia).

Treatment: gastric lavage, taking activated charcoal.

Pregnancy use

In the absence of studies, use during pregnancy and lactation is not recommended.

Similarities

El Carnitine, Carnitine, Levocarnil