Dona, 200 mg/ml 2 ml 6 pcs

DONA – has anti-inflammatory and analgesic effect, fills the endogenous deficit of glucosamine, stimulates the synthesis of proteoglycans and hyaluronic acid synovial fluid; increases the permeability of the joint capsule, restores enzymatic processes in the cells of synovial membrane and articular cartilage.

It promotes sulfur fixation in the synthesis of chondroitinous acid, facilitates normal calcium deposition in bone tissue, inhibits the development of degenerative processes in joints, restores their function, reducing joint pain.

Pharmacokinetics

When administered intramuscularly the bioavailability is 95%, rapidly distributed to tissues, half-life is about 60 hours, excreted mainly by the kidneys.

Indications

Active ingredient

Composition

Solution A: each ampoule (2 ml) contains:

active ingredient: glucosamine sulfate crystalline 502.5 mg (contains 400 mg of glucosamine sulfate and 102.5 mg of sodium chloride);

excipients: lidocaine hydrochloride 10.0 mg, water for injection to 2 ml.

The solution B: ampoule volume (1 ml) contains:

excipients: diethanolamine – 24.0 mg, water for injection up to 1 ml.

How to take, the dosage

Intramuscularly!

The drug is not intended for intravenous administration.

Mix solution B (solvent) with solution A (drug solution) in one syringe before use. The prepared drug solution is administered intramuscularly 3 ml (Solutions A + B) 3 times a week for 4-6 weeks.

Injections of the drug can be combined with oral administration of the drug in powder for preparation of solution for oral administration (sachets). The duration and scheme of treatment is prescribed by the attending physician.

Interaction

Special Instructions

Patients with chronic heart failure, arterial hypotension should use the drug with caution. Caution should be exercised in patients with allergies to seafood (shrimp, mollusks).

In patients with impaired glucose tolerance, with significant hepatic and renal insufficiency, medical supervision is necessary when using the drug.

Synopsis

Contraindications

Side effects

Tolerability of the drug is good.

In some cases, flatulence, diarrhea, constipation, allergic reactions – urticaria, itching may occur. Nausea, vomiting, somnolence, diplopia, headache, dizziness, numbness of the tongue and mucous membrane of the mouth, tremor, euphoria, disorientation, cardiac conduction disorders are possible due to the drug lidocaine content.

Overdose

Similarities