Dona, 1500 mg 20 pcs.

DONA has anti-inflammatory and analgesic effect, fills the endogenous deficiency of glucosamine, stimulates the synthesis of proteoglycans and hyaluronic acid synovial fluid; increases the permeability of the joint capsule, restores enzymatic processes in the cells of synovial membrane and articular cartilage.

It promotes sulfur fixation in the synthesis of chondroitinous acid, facilitates normal calcium deposition in bone tissue, inhibits the development of degenerative processes in joints, restores their function, reducing joint pain.

Pharmacokinetics

Absorption in the gastrointestinal tract 90%, bioavailability 26%, half-life 70 hours.

Indications

Primary and secondary osteoarthritis, osteochondrosis, spondyloarthrosis.

Pharmacological effect

Absorption in the gastrointestinal tract 90%, bioavailability 26%, half-life 70 hours.

Special instructions

When using the drug in patients with impaired glucose tolerance, with severe liver and kidney failure, medical supervision is required.

Active ingredient

Glucosamine

Composition

One sachet contains:
active substance: crystalline glucosamine sulfate 1884 mg (contains glucosamine sulfate 1500 mg and sodium chloride 384 mg); excipients: aspartame, sorbitol, carbowax 4000 (macrogol 4000), citric acid.

Pregnancy

It is not recommended to prescribe the drug during pregnancy and lactation, as well as in childhood (up to 12 years) due to the lack of scientific clinical data in this category of patients.

Contraindications

Individual hypersensitivity to glucosamine sulfate, aspartame and other components of the drug. Due to the aspartame content, it is contraindicated in patients with phenylketonuria.
It is not recommended to prescribe the drug during pregnancy and lactation, as well as in childhood (up to 12 years) due to the lack of scientific clinical data in this category of patients.

Side Effects

The drug is well tolerated, in some cases the following are possible: gastralgia, flatulence, diarrhea, constipation, allergic reactions – urticaria, itching.

Interaction

Compatible with non-steroidal anti-inflammatory drugs, paracetamol and glucocorticosteroids. Increases the absorption of tetracyclines, reduces the absorption of semisynthetic penicillins, chloramphenicol.

Overdose

Cases of overdose are unknown. Treatment: gastric lavage, symptomatic therapy.

Clinical pharmacology

DONA has an anti-inflammatory and analgesic effect, replenishes endogenous glucosamine deficiency, stimulates the synthesis of proteoglycans and hyaluronic acid in synovial fluid; increases the permeability of the joint capsule, restores enzymatic processes in the cells of the synovial membrane and articular cartilage. Promotes fixation of sulfur in the process of chondroitinsulfuric acid synthesis, facilitates normal calcium deposition in bone tissue, inhibits the development of degenerative processes in joints, restores their function, reducing joint pain.

Storage conditions

Store at a temperature not exceeding 25 ºC.
Keep out of the reach of children

Shelf life

3 years.
Do not use after the expiration date indicated on the package.

Manufacturer

Rottapharm Ltd, Ireland