Dimexide 99%, concentrate 100 ml

Pharmgroup:

Inflammatory agent for topical use.

Pharmaceutical action:

An anti-inflammatory drug for topical use, inactivates hydroxyl radicals, improves the course of metabolic processes in the inflammation focus.

It also has local anesthetic, analgesic and antimicrobial action; it has moderate fibrinolytic activity.

It penetrates through the skin, mucous membranes, the shell of microbial cells (increases their sensitivity to antibiotics) and other biological membranes and increases their permeability to drugs.

Indications

As part of complex therapy: diseases of the musculoskeletal system: rheumatoid arthritis, ankylosing spondylitis (ankylosing spondylitis), osteoarthritis deformans (in the presence of damage to periarticular tissues), reactive synovitis;
limited scleroderma, erythema nodosum, discoid lupus erythematosus, mycoses of the feet, keloid scars, thrombophlebitis, alopecia, eczema, erysipelas; bruises, sprains, traumatic infiltrates;
purulent wounds, burns, radiculitis, trophic ulcers, acne, furunculosis,
in skin plastic surgery – preservation of skin homografts.

Pharmacological effect

Pharmaceutical group:

anti-inflammatory agent for topical use.

Pharmaceutical action:

An anti-inflammatory drug for external use, inactivates hydroxyl radicals, improves the course of metabolic processes in the site of inflammation.

It also has local anesthetic, analgesic and antimicrobial effects; has moderate fibrinolytic activity.

Penetrates through the skin, mucous membranes, the membrane of microbial cells (increases their sensitivity to antibiotics) and other biological membranes, increases their permeability to drugs.

Special instructions

Some patients smell garlic in the air they breathe.

Before using the drug, it is necessary to test for tolerance to it. To do this, dimethyl sulfoxide of the required concentration is applied to the skin using a cotton swab soaked in it; the appearance of hyperemia and severe itching indicates hypersensitivity.

When stored at a temperature of 18 °C and below, crystallization of dimethyl sulfoxide occurs, which does not affect the quality of the drug. To melt the crystals, you should carefully heat the bottle with the drug in a water bath (water temperature no higher than 60 ° C).

Impact on the ability to drive vehicles and machinery.

Use of the drug in accordance with the instructions does not affect the ability to drive vehicles and engage in potentially hazardous activities that require increased concentrated attention and speed of psychomotor reactions.

Active ingredient

Dimethyl sulfoxide

Composition

Active ingredient:

Pregnancy

The use of the drug during pregnancy and breastfeeding is contraindicated.

Contraindications

Hypersensitivity, severe hepatic and/or renal failure, angina pectoris, severe atherosclerosis, glaucoma, cataracts, stroke, coma, myocardial infarction, pregnancy, lactation.

Side Effects

Allergic reactions, contact dermatitis, erythematous rashes, dry skin, mild burning, itchy dermatitis; rarely – bronchospasm.

Interaction

Increases absorption and enhances the effect of ethanol (alcohol inhibits the release of the drug), insulin (with prolonged use of the drug, the level of glucose in the blood plasma is monitored) and other drugs. Together with heparin, antibacterial agents, non-steroidal anti-inflammatory drugs. Increases the sensitivity of microorganisms to aminoglycoside and beta-lactam antibiotics; chloramphenicol, rifampicin, griseofulvin. Sensitizes the body to drugs for general anesthesia.

Overdose

Symptoms: increased dose-dependent side effects. Treatment is symptomatic.

Manufacturer

Iodine technologies and marketing, Russia