Dimethinden, gel 0.1% 50 g

Pharmacodynamics

Antihistamine, anti-allergic and antipruritic agent. Blocker of H1-histamine receptors, is a competitive histamine antagonist.

The drug reduces increased capillary permeability associated with allergic reactions. When applied to the skin the drug reduces itching and irritation caused by skin allergic reactions. It also has a strong local anesthetic effect.

It has also antikinin and weak anticholinergic effect.

When used externally the gel base allows for a quick onset of action (in a few minutes) and a mild cooling effect. Maximal effect occurs after 1-4 hours.

Pharmacokinetics

When used externally it penetrates into the skin well, systemic bioavailability is 10%.

Indications

Active ingredient

Composition

How to take, the dosage

Interaction

Special Instructions

In children from 1 month to 2 years of age, the drug should be used after consulting a doctor. In infants and young children the drug should not be used on large areas of skin, especially if there is inflammation or bleeding.

In severe itching or in case of large areas of skin, the drug should only be used after consulting a physician. Exposure to sunlight should be avoided if the drug is used on large areas of skin.

If symptoms do not decrease or increase while using the drug, you should see your doctor.

It is ineffective in itching associated with cholestasis.

The drug contains propylene glycol and benzalkonium chloride, which may cause local allergic reactions.

The effect of the drug on the ability to drive vehicles, machinery

No effect.

Contraindications

Hypersensitivity to dimethindene and other constituents of the drug, closed-angle glaucoma, prostatic hyperplasia, children under 1 month of age, especially premature infants.

Pregnancy I trimester, period of breast-feeding.

Side effects

Overdose

Pregnancy use

Similarities