Dexonal, 25 mg 10 pcs

Musculoskeletal pain (mild to moderately pronounced), algodysmenorrhea, toothache.

The drug is intended for symptomatic treatment, reducing pain and inflammation at the time of use.

Active ingredient

How to take, the dosage

The drug Dexonal® is taken orally with meals. Simultaneous intake of food slows down absorption of Dexectoprofen, therefore in case of acute pain it is recommended to use the drug at least 30 minutes before meals.

Depending on intensity of pain syndrome, the recommended dose for adults is 12.5 mg dexketoprofen (1/2 tablet Dexonal®) every 4-6 hours or 25 mg dexketoprofen (1 tablet Dexonal®) every 8 hours.

The maximum daily dose is 75 mg.

The drug is not intended for long-term therapy; the course of treatment with the drug should not exceed 3-5 days.

Patients 65 years and older

Elderly patients should take the drug starting with the lowest recommended dose. The maximum daily dose is 50 mg. If well tolerated, the doses recommended for the general population may be used.

Patients with hepatic impairment

Patients with mild to moderate hepatic impairment should take the drug starting with the minimum recommended dose. The maximum daily dose is 50 mg.

The use of the drug Dexonal® is contraindicated in patients with severe hepatic impairment.

Patients with renal failure

Patients with mild renal failure – chronic kidney disease, stage 2 (GFR 60-89 ml/min/ 1.73 m2) should take the drug starting with the lowest recommended dose. Maximum daily dose is 50 mg. The drug administration in patients with chronic kidney disease stages 3a (FFR 45-59 ml/min/1.73 m2), 3b (FFR 30-44 ml/min/1.73 m2) and 4 (FFR < 30 ml/min/1.73 m2) is contraindicated.

Interaction

Special Instructions

Contraindications

Gastric and duodenal ulcer, ulcerative colitis, Crohn’s disease, liver disease in the anamnesis, hepatic porphyria. Chronic kidney disease, stage 2 (GFR 60-89 ml/min/1.73 m2 ), chronic heart failure, arterial hypertension, significant decrease of circulating blood volume (including after surgical intervention), elderly patients older than 65 years (incl.including those receiving diuretics, weakened patients and patients with low body weight), bronchial asthma, concomitant use of glucocorticosteroids (including prednisolone), anticoagulants (including warfarin), antiplatelet agents (including acetylsalicylic acid, clopidogrel), selective serotonin reuptake inhibitors (including those with a high dose of serotonin).ч. citalopram, fluoxetine, paroxetine, sertraline), coronary heart disease, cerebrovascular disease, dyslipidemia/hyperlipidemia, diabetes, peripheral arterial disease, smoking, presence of Helicobacter pylori infection, systemic lupus erythematosus (SLE) and other systemic connective tissue diseases, long-term use of non-steroidal anti-inflammatory drugs, tuberculosis, severe osteoporosis, alcoholism, severe somatic diseases.

Side effects

Overdose

Pregnancy use

Similarities