Complivit Calcium D3 forte, mint 120 pcs
€20.22 €16.85
Pharmacotherapeutic group: calcium-phosphorus metabolism regulator.
ATC code: [A12AX].
Pharmacological properties
Pharmacodynamics
A combined drug whose action is due to its constituent components. It regulates calcium and phosphate metabolism, decreases resorption and increases bone density, compensates the lack of calcium and vitamin D3 in the body, increases absorption of calcium in intestine and reabsorption of phosphate in kidneys, promotes bone mineralization.
Calcium is involved in the formation of bone tissue, blood clotting, in maintaining stable cardiac activity, in the processes of transmission of nerve impulses.
Vitamin D3 (colecalciferol) – promotes the absorption of calcium in the intestine, the formation and mineralization of bone and dental tissue.
The use of calcium and vitamin D3 prevents increased production of parathyroid hormone, which is a stimulant of increased bone resorption.
Pharmacokinetics
Vitamin D3 is absorbed in the small intestine. Calcium is absorbed in ionized form in the proximal small intestine through an active, D-vitamin dependent transport mechanism.
Indications
Prevention and comprehensive therapy of osteoporosis (menopausal, senile, “steroid”, idiopathic) and its complications (bone fractures).
Active ingredient
Composition
Calcium 500 mg, (as calcium carbonate) 1.25 g
Calciferol (vitamin D3) 0.01 mg (400 IU)
(in terms of 100% colocalciferol)
(as granulate, containing colocalciferol – 0,27 %, D,L-alpha-tocopherol – 0,0275 %, medium-chain triglycerides – 10,7 %, sucrose – 36 %, acacia gum – 22 %, corn starch – 27 %, calcium phosphate (E 341) – 0,5 %, water up to 100 %).
Auxiliary substances: Lactose monohydrate – 333.118 mg/333.118 mg, povidone (polyvinylpyrrolidone medium molecular weight, povidone K-30) – 68.24 mg/68.24 mg, polysorbate-80 – 0 mg/1.731 mg, potato starch – 18.969 mg/18.969 mg, croscarmellose sodium – 45,713 mg/50.282 mg, citric acid monohydrate – 3.325 mg/3.325 mg, aspartame (E 951) – 5.95 mg/5.95 mg, magnesium stearate – 15.75 mg/15.75 mg, orange flavoring – 8.925 mg or peppermint leaf oil – 2.625 mg.
How to take, the dosage
Over the mouth, chewed or swallowed whole, mostly with meals.
Adults: for the treatment of osteoporosis – 1 tablet 2-3 times a day, for the prevention of osteoporosis – 1 tablet 2 times a day.
For the replenishment of calcium and/or vitamin D3 deficiency:
Adults and children over 12 years – 1 tablet 1-2 times a day.
Interaction
Vitamin D3 activity may decrease with concomitant use of phenytoin or barbiturates.
Concomitant treatment with cardiac glycosides requires ECG and clinical monitoring, because calcium preparations may potentiate therapeutic and toxic effects of cardiac glycosides.
Calcium and vitamin D3 preparations may increase absorption of tetracyclines from the gastrointestinal tract. Therefore, the time interval between doses should be at least 3 hours.
In order to prevent reduced absorption of bisphosphonates or sodium fluoride, it is recommended that Complivit® Calcium D3 Forte not be taken more than two hours after taking them.
Glucocorticosteroids decrease calcium absorption, therefore treatment with glucocorticosteroids may require increasing the dose of Complivit® Calcium D3 Forte.
Concomitant treatment with colesteramine preparations or mineral or vegetable oil-based laxatives may decrease vitamin D3 absorption.
Concomitant use of thiazide-type diuretics increases the risk of hypercalcemia because they increase the tubular reabsorption of calcium. In contrast, furosemide and other loop diuretics increase renal calcium excretion.
Special Instructions
In order to avoid an overdose, additional vitamin D3 intake from other sources must be considered.
Complivit® Calcium D3 Forte contains aspartame, which is transformed in the body into phenylalanine, so the drug should not be taken by patients suffering from phenylketonuria.
During treatment it is necessary to monitor constantly urinary calcium excretion and plasma calcium and creatinine concentrations (in case of calcium exceeding 7.5 mmol/day (300 mg/day), the dose should be reduced or the therapy should be stopped).
Contraindications
Hypersensitivity to the components of the drug (including Lactose intolerance, lactase deficiency, glucose-galactose malabsorption), hypercalcemia, hypercalciuria, calcium nephrourolithiasis, hypervitaminosis D, decalcifying tumors (myeloma, bone metastases, sarcoidosis), osteoporosis due to immobilization, phenylketonuria (contains aspartame), pulmonary tuberculosis (active form), chronic renal failure, children under 3 years of age.
Side effects
Overdose
In case of signs of overdose, consult a physician.
Symptoms: thirst, polyuria, decreased appetite, nausea, vomiting, constipation, dizziness, weakness, headache, fainting, coma; with long-term use: vascular and tissue calcinosis.
Treatment: administration of large amounts of fluid, use of “loop” diuretics (e.g., furosemide), glucocorticosteroids, calcitonin, bisphosphonates.
Pregnancy use
Similarities
Weight | 0.275 kg |
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Shelf life | 3 years. |
Conditions of storage | At a temperature not higher than 25 ° C. Keep out of reach of children. |
Manufacturer | Pharmstandard-UfaVITA, Russia |
Medication form | chewable tablets |
Brand | Pharmstandard-UfaVITA |
Other forms…
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