Complivit Calcium D3 for kids, 43 g

Combination drug designed to replenish calcium and vitamin D₃ deficiency in the body.

Pharmacodynamics. Calcium is involved in the formation of bone tissue, increases its density, participates in the mineralization of teeth, in the regulation of nerve conduction and muscle contractions, in maintaining the stability of cardiac activity, in the process of blood clotting.

Vitamin D₃ (colecalciferol) regulates calcium and phosphorus metabolism in the body, increases calcium absorption in the intestine, promotes bone mineralization, formation of bone skeleton and teeth in children. The drug reduces the production of parathyroid hormone, which is a stimulant of increased bone resorption.

Indications

Prevention of calcium and vitamin D3 deficiency in young children.

Active ingredient

Composition

How to take, the dosage

Complivit Calcium D3 for kids is taken orally, with meals.

The medicinal form is specially designed for children under 3 years of age.

Preparing the powder suspension:
In the bottle containing the powder, add boiled and cooled water to 2/3 of the volume of the bottle, mix thoroughly (for 1-2 minutes). Add boiled and cooled water to the volume of 100 ml (up to the neck of the vial) and stir again. Shake the contents of the bottle before each administration.

5 ml of the suspension contains calcium carbonate in terms of elemental calcium – 200 mg, colecalciferol – 50 IU.

Children over 1 year of age – 5-10 ml 1 time daily; children under 1 year of age – 5 ml of suspension 1 time daily, upon physician’s recommendation. Administration of the drug in other age groups is carried out if necessary in appropriate doses upon the doctor’s recommendation.

The duration of the course of prophylaxis is 1 month, a longer course – by doctor’s prescription.

Interaction

Calcium and vitamin D3 drugs reduce absorption of bisphosphonates, digoxin, iron drugs and tetracycline antibiotics (an interval of at least 2-3 hours between doses is necessary).

Possible enhancement of the effect of cardiac glycosides (ECG and patient’s condition must be monitored during concomitant administration).

Phenytoin, barbiturates, primidone decrease the effect of vitamin D3 by increasing its metabolism.

Vitamin A, tocopherol, ascorbic acid, pantothenic acid, thiamine, riboflavin weaken the toxic effects of vitamin D3.

Glucocorticosteroids reduce the absorption of calcium ions in the intestine.

Colestyramine, colestipol and mineral oils reduce absorption of vitamin D3 and require increasing its dosage.

Thiazide diuretics increase the risk of hypercalcemia.

Vitamin D increases absorption of phosphorus-containing drugs and the risk of hyperphosphatemia. When concomitant use with sodium fluoride the interval between doses should be at least 2 hours; with oral forms of tetracyclines – at least 3 hours.

Long-term therapy with vitamin D3 against concomitant use of Al3+ and Mg2+-containing antacids increases their blood concentrations and the risk of intoxication (especially in the presence of CKD).

The concomitant use with other vitamin D analogues and calcium preparations increases the risk of hypervitaminosis D.

Special Instructions

In order to avoid overdose do not use Complivit calcium D3 simultaneously with vitamin complexes containing calcium and vitamin D3.

When prophylactic use of vitamin D3 it is necessary to be aware of the possibility of overdose, especially in children (do not prescribe more than 10-15 mg per year).

Long-term use at high doses leads to chronic hypervitaminosis of D3. With long-term treatment it is necessary to monitor the concentration of Ca2+ in blood and urine (especially if combined with thiazide diuretics).

It must be kept in mind that sensitivity to vitamin D varies from patient to patient, and in a number of patients even therapeutic doses may cause hypervitaminosis.

The sensitivity of newborns to vitamin D varies, and some may be sensitive even to very low doses, so prophylaxis should be under medical supervision.

Breastfed newborns, especially those born to mothers with dark skin and/or who have received insufficient insolation, are at high risk for vitamin D deficiency.

Contraindications

Hypersensitivity, hypercalcemia, hypercalciuria, calcium nephrolithiasis, hypervitaminosis D, decalcifying tumors (myeloma, bone metastases, sarcoidosis), immobilization-induced osteoporosis, active pulmonary tuberculosis; Sucrose/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.

WARNING

Renal failure, benign granulomatosis, taking cardiac glycosides and thiazide diuretics, pregnancy, lactation.

Side effects

Allergic reactions. When using the drug in the recommended doses no other side effects have been revealed. In case of exceeding the recommended doses or concomitant use of other drugs containing calcium hypercalcemia and hypercalciuria (increase in calcium content in blood and urine) may occur.

Possible side effects of vitamin D3 also include decreased appetite, polyuria, constipation, headache, myalgia, arthralgia, increased BP, arrhythmias, impaired renal function, exacerbation of tuberculosis in the lungs.

Possible side effects of calcium carbonate also include: gastralgia, constipation or diarrhea, flatulence, nausea, secondary increase in gastric secretion.

Overdose

Symptoms: thirst, polyuria, decreased appetite, nausea, vomiting, constipation, dizziness, weakness, headache, fainting, coma; with prolonged use vascular and tissue calcinosis. Laboratory indicators in overdose: hypercalciuria, hypercalcemia.

Treatment: discontinuation of the drug, consult a physician, diet with calcium restriction, rehydration, diuretics, glucocorticosteroids, in severe cases hemodialysis.

Pregnancy use

In pregnancy and during breastfeeding the use of the drug is possible under the doctor’s recommendation.

The daily dose should not exceed 1500 mg of calcium and 600 ME of vitamin D3.

Hypercalcemia in overdose and excessive vitamin D3 intake during pregnancy can have adverse effects on the developing fetus.

Similarities