Coldact Flux Plus, capsules 10 pcs

A combined drug of prolonged action.

Chlorphenamine has anti-allergic effect, eliminates lacrimation, itching of the eyes and nose.

Paracetamol has antipyretic and analgesic effect: it reduces pain syndrome caused by colds – sore throat, headache, muscle and joint pain, reduces fever.

Phenylephrine has a vasoconstrictor effect – reduces swelling and hyperemia of the mucous membranes of the upper airways and sinuses.

Indications

Symptomatic treatment of “colds”, flu, SARS (fever syndrome, pain syndrome, rhinorrhea).

Active ingredient

Composition

Active ingredients:

Associate ingredients:

Talc 68.25 mg,

Hypromellose 4.5 mg,

Ethylcellulose 29 mg,

diethyl phthalate 5.8 mg,

microcrystalline cellulose 28.01 mg,

povidone 6.41 mg,

purified water* q.s.,

isopropanol* q.s,

sodium disulfite 0.16 mg,

dinatrium edetate 0.32 mg,

pain dye (Ponceau 4R) 0.35 mg,

sunset yellow dye 0.01 mg,

quinoline yellow dye 0.08 mg,

Non Pareil Seeds18/22 pellets (sugarcane: sucrose, starch treacle) 124.11 mg.

Capsule shell:

Gelatin q.s. up to 100%,

purified water 14-15%,

methyl parahydroxybenzoate 0.2%,

Azorubin dye 0.35 %,

Punsenic dye (Ponceau 4R) 0.47 %.

*lost in the production process

How to take, the dosage

Adults and children over 12 years of age – 1 capsule every 12 hours for 3-5 days.

The duration of use:

Interaction

The risk of hematotoxic effects increases.

The risk of hematotoxic effects of paracetamol increases with the simultaneous administration of barbiturates, diphenine, carbamazepine, rifampicin, zidovudine and other inducers of microsomal liver enzymes. Increases the effects of sedative drugs, ethanol , monoamine oxidase inhibitors.

Antidepressants, phenothiazine derivatives, antiparkinsonian and antipsychotic drugs

Antidepressants, phenothiazine derivatives, antiparkinsonian and antipsychotic drugs increase the risk of urinary retention, dry mouth, constipation.

Glucocorticosteroids

Glucocorticosteroids increase the risk of glaucoma. Paracetamol reduces the effectiveness of uricosuric drugs. Chlorphenamine concomitantly with furazolidone may lead to a hypertensive crisis, agitation of hyperrexia.

Tricyclic antidepressants

Tricyclic antidepressants increase the adrenomimetic effects of phenylephrine , concomitant administration of halothane increases the risk of ventricular arrhythmias. It reduces the hypotensive effect of guanethidine, which in turn increases the alpha-adrenergic stimulating activity of phenylephrine.

Special Instructions

Do not continue to take Coldact Flux Plus without a physician’s consultation if the fever persists for more than 3 days.

Without a physician’s indication, do not use in patients treated with other drugs, particularly MAO inhibitors. If in spite of taking the drug, the disease is accompanied by persistent fever or recurrent fever, it is necessary to consult a physician. Do not take with alcohol and should not be combined with other drugs containing paracetamol. Sleeping pills, tranquilizers and other psychotropic drugs are undesirable when using Coldact Flux Plus.

It distorts laboratory values for quantitative determination of glucose and uric acid in plasma. In case of long-term treatment, peripheral blood parameters and functional state of the liver are monitored.

Impact on driving and operating machinery

During the treatment it is necessary to refrain from driving vehicles and engaging in potentially dangerous activities requiring increased concentration and quick psychomotor reactions.

Contraindications

With caution: congenital hyperbilirubinemia (Gilbert, Dubin-Johnson and Rotor syndromes), bronchial asthma and chronic obstructive pulmonary disease.

Side effects

Rarely

Hepatotoxic and nephrotoxic effects are possible with prolonged use in high doses.

Overdose

Symptoms (conditioned by the presence of paracetamol in the composition) appear after taking more than 10-15 g: pale skin, decreased appetite, nausea, vomiting, hepatonecrosis, increased liver transaminases activity, increased prothrombin time.

Treatment: gastric lavage in the first 6 h, administration of SH-group donators and precursors of glutathione-methionine synthesis in 8-9 h after overdose and N-acetylcysteine in 12 h.

In case of accidental overdose, seek medical attention immediately, regardless of whether or not any symptoms of overdose are noted.

Pregnancy use

Coldact Flux Plus capsules are not recommended for use during pregnancy and lactation.

Pediatric use

It is contraindicated in children under 12 years of age.