Cloveit, 0.05% cream 25 g

GCS for external use.

Prevent marginal accumulation of neutrophils, decrease inflammatory exudation and production of lymphokines, inhibit macrophage migration, decrease the intensity of infiltration and granulation processes, have local anti-inflammatory, antipruritic, anti-allergic anti-exudative effects.

Indications

Active ingredient

Composition

1 g of cream contains:

Active ingredients:

clobetasol propionate 500 µg.

Auxiliary ingredients:

White petroleum jelly, 252 mg;

propylene glycol, 100 mg;

Polysorbate 40 – 53 mg;

dinatrium edetate – 0.2 mg;

Chlorocresol – 1 mg;

Glycerol monostearate – 31 mg;

Liquid paraffin – 23 mg;

Ceto stearyl alcohol (cetyl alcohol and stearyl alcohol in the ratio 6:4) – 69 mg;

octanoic and decanoic acid triglycerides – 15 mg;

sodium citrate – 0.5 mg;

colloidal silicon dioxide – 1 mg;

citric acid – 0.5 mg;

chemoderm flavoring 841 – 0.3 mg;

purified water – up to 1000 mg.

How to take, the dosage

A small amount of cream is applied to the affected skin surface 1-2 times a day, rubbing lightly.

The product should not be used under an occlusive dressing and should not be used without a break for more than 2 weeks.

Special Instructions

Long-term use should be avoided. Prolonged use on large areas of the skin increases the frequency of adverse effects and the risk of edema, arterial hypertension, hyperglycemia, reduced body resistance.

In external use of clobetasol propionate, inhibition of the pituitary-adrenal system is possible. This is expressed as a decrease in pituitary production of ACTH, a decrease in blood cortisol levels and the development of iatrogenic Cushing’s syndrome. The above-mentioned changes go away after discontinuation of treatment. Adrenal function should be monitored regularly by determining cortisol levels in blood and urine after adrenal stimulation by ACTH.

If an infection develops in the area of application, appropriate antibacterial or antifungal treatment should be prescribed. If symptoms of infection persist, Cloveit should be discontinued until the infection is cured.

Application of the drug on the skin in the eyelid area in patients with closed- or open-angle glaucoma, with cataracts should be avoided due to the risk of exacerbation of the disease. The drug should be used on the face, axillae and groin only in cases of extreme necessity, given the increased absorption and increased risk of side effects (telangiectasia, perioral dermatitis).

With caution, use with atrophic conditions of subcutaneous fatty tissue, especially in the elderly.

Cloveit may increase the effect of immunosuppressant drugs and weaken the effect of immunostimulant drugs.

Contraindications

Side effects

Local reactions: acne, steroid purpura, inhibition of epidermal growth, subcutaneous atrophy, dry skin, hypertrichosis or alopecia, hypo- or hyperpigmentation of the skin, skin atrophy and stretch marks, telangiectasia, perioral dermatitis, inflammation of hair follicles, secondary infection.

Systemic effects: edema, arterial hypertension, decreased resistance (resorptive effect when used under an occlusive dressing).

Allergic reactions: rare – urticaria or maculopapular rash.

Sensory organs: glaucoma, cataracts (when used on the eyelid skin).

Similarities