Ciprolet, 250 mg 10 pcs

Ciprolet is an antimicrobial drug of the group of fluoroquinolones.
The mechanism of action of ciprofloxacin is associated with its effect on bacterial DNA-hypase (topoisomerase),
which plays an important role in the reproduction of bacterial DNA.

Indications

Active ingredient

How to take, the dosage

The dose of Ciprolet depends on the severity of the disease, type of infection, body condition, age, body weight and renal function.

In uncomplicated renal and urinary tract diseases, 250 mg 2 times a day, and in severe cases – 500 mg 2 times a day.

In moderate lower respiratory tract diseases, 250 mg 2 times a day, and in more severe cases, 500 mg 2 times a day.

A single administration of Ciprolet® in a dose of 250-500 mg is recommended for treatment of gonorrhea.

In gynecological diseases, enteritis and colitis with severe course and high fever, prostatitis,

Osteomyelitis, 500 mg 2 times a day is indicated (for treatment of common diarrhea a dose of 250 mg 2 times a day can be used).

The tablets should be taken on an empty stomach with plenty of fluid.

The duration of treatment depends on the severity of the disease, but treatment should always continue for at least 2 more days after symptoms disappear.

The duration of treatment is usually 7-10 days.

Interaction

In concomitant use of Ciprolet with didanosine absorption of ciprofloxacin is reduced due to the formation of complexes of ciprofloxacin with aluminum and magnesium salts contained in didanosine.

Concomitant administration of Ciprolet and theophylline may lead to increased plasma concentrations of theophylline,

due to competitive inhibition in cytochrome P450 binding sites, which leads to increased T1/2 of theophylline and increased risk of theophylline-associated toxic effects.

The simultaneous administration of antacids as well as drugs containing aluminum, zinc, iron, or magnesium ions may decrease absorption of ciprofloxacin; therefore, the interval between administration of these drugs should be at least 4 hours.

The simultaneous use of Ciprolet and anticoagulants prolongs bleeding time.

In concomitant use of Ciprolet and cyclosporine the nephrotoxic effect of the latter is increased.

Special Instructions

Synopsis

Contraindications

Side effects

Overdose

Treatment: the patient’s condition should be closely monitored, gastric lavage should be performed, the usual first aid measures should be carried out, and adequate fluid intake should be ensured.

Only a small (less than 10%) amount of the drug may be eliminated by hemo- or peritoneal dialysis.

A specific antidote is not known.

Pregnancy use

Similarities