Cinocap, cream 0.2% 50 g

Zinc pyrithione has anti-inflammatory, antibacterial and antifungal activity. Antibacterial activity of zinc pyrithione is shown against a number of Gram-positive and Gram-negative bacteria (Streptococcus spp., Staphylococcus spp., Escherichia coli, Pseudomonas aeruginosa, Proteus spp.)

Zinc pyrithione reduces intracellular ATP level, promotes depolarization of cell membranes, causing death of fungi and bacteria. Antifungal activity is especially pronounced against fungi of the genus Malassezia (formerly Pityrosporum ovale and Pityrosporum orbiculare) causing inflammation and excessive flaking in dandruff, seborrheic dermatitis, psoriasis and other skin diseases. The mechanism of anti-inflammatory action is not studied.

Pharmacokinetics

The systemic absorption is insignificant. The drug is detected in the blood in trace amounts.

Indications

Psoriasis

atopic dermatitis (eczema, neurodermatitis)

seborrheic dermatitis

dry skin

Pharmacological effect

Pyrithione zinc has anti-inflammatory, antibacterial and antifungal activity. The antibacterial activity of zinc pyrithione is manifested against a number of gram-positive and gram-negative bacteria (Streptococcus spp., Staphylococcus spp., Escherichia coli, Pseudomonas aeruginosa, Proteus spp.)

Pyrithione zinc reduces the intracellular level of ATP, promotes depolarization of cell membranes, causing the death of fungi and bacteria. Antifungal activity is especially pronounced against fungi of the genus Malassezia (formerly Pityrosporum ovale and Pityrosporum orbiculare), which cause inflammation and excessive flaking in dandruff, seborrheic dermatitis, psoriasis and other skin diseases. The mechanism of anti-inflammatory action has not been studied.

Pharmacokinetics

Systemic absorption is negligible. The drug is found in the blood in trace amounts.

Active ingredient

Pyrithione zinc

Composition

100 g of cream contains:

active substance – zinc pyrithione (in terms of 100% substance) – 0.2 g (0.2%);

excipients:
macrogol cetostearate,
cetostearyl alcohol,
liquid paraffin (vaseline oil),
propylene glycol, dexpanthenol (D-Panthenol),
sodium dihydrogen phosphate dihydrate,
sodium hydrogen phosphate dodecahydrate,
purified water.

Contraindications

Hypersensitivity, children under 1 year of age.

Side Effects

The drug is usually well tolerated.

Allergic reactions are sometimes observed.

Storage conditions

In a dry place, at a temperature of 4–25 °C

Shelf life

2 years

Manufacturer

Lecco CJSC, Russia