Chlorhexidine, vaginal suppositories 16 mg 10 pcs

Chlorhexidine is an antiseptic agent for topical use active against Gram-positive and Gram-negative protozoan bacteria and viruses, including Treponema pallidum Chlamidia spp. Ureaplasma spp. Neisseria gonorrhoeae Trichomonas vaginalis Gardnerella vaginalis Bacteroides fragilis Herpes simplex virus type 2. Some strains of Pseudomonas spp. Proteus spp. as well as acid-resistant forms of bacteria spores bacteria fungi. Chlorhexidine does not impair the functional activity of lactobacilli. Maintains activity although somewhat reduced in the presence of blood pus and other biological fluids.

Pharmacokinetics:
In intravaginal application practically does not absorb and has no systemic action.

Indications

– treatment of vaginitis (including acute nonspecific mixed trichomonas);

– prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases before childbirth and abortion before and after installation of an intrauterine device (IUD) before and after diathermocoagulation of the cervix before intrauterine examinations);

– prevention of sexually transmitted infections (chlamydia, ureaplasmosis, genital herpes, syphilis, gonorrhea, trichomoniasis).

Pharmacological effect

Pharmacodynamics:
Chlorhexidine is an antiseptic drug for topical use that is active against protozoa gram-positive and gram-negative bacteria, viruses including Treponema pallidum Chlamydia spp. Ureaplasma spp. Neisseria gonorrhoeae Trichomonas vaginalis Gardnerella vaginalis Bacteroides fragilis Herpes simplex virus type 2. Some strains of Pseudomonas spp are weakly sensitive to the drug. Proteus spp. and acid-resistant forms of bacteria, spores of bacteria and fungi are also resistant. Chlorhexidine does not interfere with the functional activity of lactobacilli. Retains activity, although somewhat reduced in the presence of blood, pus and other biological fluids.

Pharmacokinetics:
When used intravaginally, it is practically not absorbed and has no systemic effect.

Special instructions

Toilet of the external genitalia does not affect the effectiveness and tolerability of suppositories, since the drug is used intravaginally.
The drug is intended for intravaginal use in adults. If allergic reactions or irritation occur at the site of drug administration, treatment is stopped. To prevent infection, simultaneous treatment of sexual partners is necessary. During treatment for bacterial vaginosis, it is recommended to abstain from sexual intercourse. It is possible to use the drug during menstruation, since the drug retains its activity, although somewhat reduced, in the presence of blood, pus and other biological fluids.
Impact on the ability to drive vehicles and machinery
The use of the drug does not affect driving or engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Active ingredient

Chlorhexidine

Composition

Active substance: chlorhexidine bigluconate – 16 mg (chlorhexidine bigluconate is used in the form of a solution (concentration 20%)).

Excipients: macrogol-1500 (polyethylene glycol 1500) – 2533.3 mg, macrogol-400 (polyethylene glycol 400) – 225.2 mg, macrogol-4000 (polyethylene glycol 4000) – 56.3 mg.

Pregnancy

The use of the drug during pregnancy and lactation is possible if the expected benefit to the mother outweighs the potential risk to the fetus and child.

Contraindications

childhood;
hypersensitivity to the components of the drug.

With caution: pregnancy, lactation period.

Side Effects

Allergic reactions and itching are possible after discontinuation of the drug.

If any of the side effects indicated in the instructions get worse or you notice any other side effects not listed in the instructions, notify your doctor.

Interaction

Concomitant use with iodine-containing drugs is not recommended if they are used intravaginally.

Chlorhexidine is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally. Toilet of the external genitalia does not affect the effectiveness and tolerability of Chlorhexidine vaginal suppositories, because the drug is used intravaginally.

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25°C.

Shelf life

2 years.

Manufacturer

Pharmproject, Russia