Chiloparin-comod ophthalmic solution, 10 ml

Burning, itching, lacrimation, a feeling of a foreign body, or a feeling of dryness are symptoms of eye irritation. You rub your eyes, but the unpleasant symptoms persist. This is a sign that the surface of your eye is not sufficiently moist. The surface of a healthy eye is covered with a smooth, uniform tear film that keeps the tissues in good functional condition and washes away any dust or dirt particles. Some conditions put extra strain on the eye and impair the physiological function of the tear film. This can be caused by being in an air-conditioned room, working intensely with a computer, or being in a dusty environment. Tear secretion decreases with age.

Hiloparin-Comod® Ophthalmic Moisturizing Solution combines the advantages of two physiological substances. Thanks to their physical and chemical properties these substances are particularly suitable for the restoration of the tear film on the surface of the eye. HILOPARIN-COMOD® solution contains sodium hyaluronate, which is a natural substance. Sodium hyaluronate is a physiological polysaccharide compound found both in the tissues of the eye and in other tissues and fluids of the human body.

The special physical and chemical property of sodium hyaluronate molecules is their expressed ability to bind and retain water molecules in volumes many times greater than its own weight. Its long molecular chains form water storages, and its gel-like structure changes its viscosity, adapting it to the movement of the eye lids. The elasticity and thixotropic properties of the solution guarantee, on the one hand, the formation of a stable moisturizing film on the ocular surface, and on the other hand, it does not impede vision between blinks of the eyelids. The aqueous solution of sodium hyaluronate has the necessary viscosity and high adhesive properties to the front surface of the eye (cornea and conjunctiva).

Sodium heparin is also a natural substance similar in chemical structure to sodium hyaluronate. In addition, the chemical structure of sodium heparin bears a great resemblance to the physiological mucin of the tear film, it is also surrounded by a significant amount of water. These properties of sodium heparin further support the moisturizing effect of sodium hyaluronate, thereby creating the necessary conditions for regeneration of the ocular surface epithelium. Sodium hyaluronate and heparin restore the normal condition of the cornea and conjunctiva; together with natural tears these components will additionally moisten the ocular surface.

The result is a stable tear film that protects the eye from the adverse effects of the environment. Thanks to the absence of preservatives and the content of natural substances HILOPARIN-COMOD® solution is generally well tolerated.

Hiloparin Comod® solution is housed in the ingenious Comod® container which is an ingenious system of reservoirs and valves to ensure that no outside air enters and that consistent droplets are removed regardless of the amount of force applied.

The metal parts and valves of the container which are in contact with the solution are partially coated with a thin layer of silver which together with the absolute air-tightness of the system ensures that the HILOPARIN-COMOD® solution is sterile in the absence of preservatives.

This prevents possible undesired effects of the preservatives on the eye tissue and ensures good tolerance of HILOPARIN-COMOD® solution even with prolonged use.

Indications

Active ingredient

Composition

1 ml of HILOPARIN-COMOD® solution contains:

Sodium hyaluronate (sodium salt of hyaluronic acid) – 1 mg,

Sodium heparin – 1300 IU

Citric acid anhydrous, sodium citrate dihydrate, glycerol, water.

How to take, the dosage

Hiloparin-Comod® solution should be injected into the conjunctival sac of each eye 3 times daily in 1 drop. HILOPARIN-COMOD® solution may be injected more frequently if necessary.

The frequency of HILOPARIN-COMOD® solution application is determined individually depending on your feelings and in compliance with the recommendations of your ophthalmologist. If you use HILOPARIN COMOD® very frequently (e.g. more than 10 times per day), please consult your ophthalmologist. If you continue to have symptoms or discomfort for several days after using HILOPARIN COMOD® Solution, please also consult an ophthalmologist.

The COMPOD® System contains and dispenses 10 ml of HILOPARIN-COMOD® which is the equivalent of about 300 drops of solution.

After the entire contents have been used a new filled container of HILOPARIN-COMOD® solution must be purchased as the system is not designed for reuse.
There is no limit to the duration of use of HILOPARIN-COMOD® solution.

To use

Please remove the cap before each application.

Please turn the container upside down and press the base of the container repeatedly until the first drop appears at the tip of the drip tip before using HILOPARINCOMOD® solution for the first time. The system is then ready to use. Hold the bottle with the dropper facing down, with your thumb near the neck of the bottle and the rest of your fingers on the base.

When applying HILOPARIN-COMOD® solution, hold the bottle with the drip pan facing downward, pressing the base down quickly and vigorously. This activates the drip mechanism and only one drop of solution is ejected. Due to the special design of the valves in the KOMOD® system the droplet size and pull-out rate remain the same even with very high pressure on the base of the container.

Hold the hand holding the container with your other hand as shown.

Tilt your head slightly back, gently move your finger away from your lower eyelid, and drop one drop into the conjunctival sac as described above. Slowly close your eyes, letting the fluid spread evenly over the surface of the eye.

When the procedure is complete, place the cap tightly over the dropper. Make sure that the pipette tip is dry.

Avoid contact of the tip of the dropper with the surface of the eye and the skin when injecting.

The KOMOD® system dispenses 10 ml of solution, which is equivalent to approximately 300 drops. For technical reasons, a small amount of liquid remains in the bottle at the end of dispensing.

The KOMOD® system is designed for individual use.

Because HILOPARIN COOMOD® solution does not contain preservatives, it is well tolerated even with long term use. In very rare cases hypersensitivity reactions such as burning or intense lacrimation may occur, but these immediately disappear when HILOPARIN-COMOD® Solution is discontinued. In very rare cases, allergic skin reactions caused by heparin have been reported.

HILOPARIN-COMOD® Solution can be used when contact lenses are worn. There are no restrictions on the use of HILOPARIN-COMOD® Solution in children and pregnant or breastfeeding women.

Interaction

When used together with ophthalmic drugs, a pause of at least 30 minutes is recommended between HILOPARIN-COMOD® solution and the use of eye drops, and HILOPARIN-COMOD® solution should always be used last. Eye ointments should always be used after HILOPARIN-COMOD® solution has been injected.

If used together with eye drops containing gentamicin, a pause of at least 1 hour between injections of both products is recommended because gentamicin forms a visible precipitate in the ocular tissues upon direct contact with heparin.

When wearing contact lenses it is recommended that HILOPARIN-COMOD® Solution be used 30 minutes after contact lens wear to prevent possible incompatibility reactions between contact lens care products and HILOPARIN-COMOD® Solution.

Special Instructions

Contraindications