Sneezing, Runny nose (rhinitis), Allergic rhinitis, Increased lacrimation, Allergy, Allergic conjunctivitis, Dermatosis, Skin itching, Neurodermitis, Pollinosis, Urticaria
- Seasonal and year-round allergic rhinitis;
- allergic conjunctivitis;
- pollenosis (hay fever);
- hives, including chronic idiopathic urticaria;
- itching allergic dermatoses (atopic dermatitis, neurodermitis);
- angioedema (Quincke’s edema).
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Indications
Seasonal and year-round allergic rhinitis;
allergic conjunctivitis;
hay fever (hay fever);
urticaria, including chronic idiopathic urticaria;
itchy allergic dermatoses (atopic dermatitis, neurodermatitis);
angioedema (Quincke’s edema).
Pharmacological effect
Pharmacodynamics
Special instructions
If the dose is exceeded 10 mg/day, the ability to react quickly may deteriorate.
In recommended doses, it does not enhance the effect of ethanol (at a concentration of no more than 0.8 g/l),
however, it is recommended to avoid its use during treatment.
For children (from 2 years old) Cetrin® is used in the form of syrup.
During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Active ingredient
Cetirizine
Composition
Each film-coated tablet contains:
Active ingredient:
cetirizine dihydrochloride 10 mg.
Excipients:
lactose,
corn starch,
povidone (K-30),
magnesium stearate;
film shell:
hypromellose,
macrogol 6000,
titanium dioxide,
talc,
sorbic acid,
polysorbate 80,
Dimethicone
Pregnancy
Pregnancy
When analyzing prospective data on pregnancy outcomes, no cases of malformations, embryonic and neonatal toxicity with a clear cause-and-effect relationship were identified.
Contraindications
Hypersensitivity (including to hydroxyzine);
pregnancy, breastfeeding period;
children under 6 years of age (for this dosage form).
With caution:
Chronic renal failure (moderate and severe severity – correction of the dosage regimen is required), old age (possible decrease in glomerular filtration).
Side Effects
Cetrin® is usually well tolerated.
Interaction
No pharmacokinetic interactions were detected with pseudoephedrine, cimetidine, ketoconazole, erythromycin, azithromycin, diazepam and glipizide.
Co-administration with theophylline (400 mg/day) led to a 16% decrease in the total clearance of cetirizine (theophylline kinetics did not change).
Overdose
Symptoms:
drowsiness; with a significant overdose of the drug (exceeding the therapeutic dose by 30-40 times in adults and children) – drowsiness, anxiety, itching, rash, urinary retention, fatigue, tremor, tachycardia.
In all cases, complete normalization of the condition was observed.
Treatment:
gastric lavage; if necessary, symptomatic therapy. There is no specific antidote.
Hemodialysis is ineffective.
Storage conditions
At a temperature not exceeding 25 °C.
Keep out of the reach of children!
Shelf life
2 years
Manufacturer
Dr. Reddy’s Laboratories Ltd, India
Shelf life | 2 years |
---|---|
Conditions of storage | At a temperature not exceeding 25 ° C. Keep out of reach of children! |
Manufacturer | Dr. Reddy's, India |
Medication form | pills |
Brand | Dr. Reddy's |
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