Carnitine chloride, 100 mg/ml concentrate 5 ml 10 pcs
€19.20 €16.00
Carnitine chloride is an anabolic agent of non-steroidal nature.
The drug stimulates metabolic processes by participating in various parts of energy metabolism, has an anabolic, antihypoxic and antithyroid effect, activates lipid metabolism, stimulates regeneration, increases appetite. Carnitine is a natural substance related to the B vitamins.
It is a cofactor of metabolic processes to maintain the activity of CoA.
Limits basic metabolism, slows down the breakdown of protein and carbohydrate molecules. It promotes penetration through mitochondrial membranes and breakdown of long-chain fatty acids (palmitic acid and others) to form acetyl-CoA, which is necessary for pyruvate carboxylase activity during gluconeogenesis, ketone bodies formation, choline and its esters synthesis, oxidative phosphorylation and ATP formation. Mobilizes fat (the presence of three labile methyl groups) from fat depots.
Contestively displacing glucose it activates the fatty acid metabolic shunt whose activity is not limited by oxygen (unlike aerobic glycolysis) and therefore the drug is effective in acute hypoxia (including brain) and other critical conditions.
It has a neurotrophic effect, inhibits apoptosis, limits the affected area and restores the structure of nervous tissue.
Normalizes protein and fat metabolism, increased basic metabolism in hyperthyroidism (being a partial antagonist of thyroxine).
The preparation restores alkaline blood reserve, does not influence the blood coagulation system, reduces ketoacid formation, increases tissue resistance to the influence of toxic decay products, activates aerobic processes and inhibits anaerobic glycolysis, has antihypoxic properties, stimulates and accelerates reparative processes.
Indications
Active ingredient
Composition
1 ml of the solution contains:
100 mg of carnitine chloride and up to 1 ml of water for injection.
How to take, the dosage
The drug is administered intravenously by drip slowly (not more than 60 drops per minute!). Before injection, the contents of one or two ampoules – 5-10 ml of carnitine chloride 10% solution (0.5-1 g) – are diluted in 200 ml of 0.9% sodium chloride solution for injection.
In acute disorders of cerebral circulation, 1 g once daily for the first three days, and then 0.5 g daily for 7 days. After 10-12 days repeated courses are recommended – 0.5 g once a day for 3-5 days.
When the preparation is administered in subacute and recovery periods, in discirculatory encephalopathy and various brain lesions the patients are administered 0.5-1 g (1-2 ampoules) of the preparation once a day for 3-5 days.
If necessary the second course is prescribed in 12-14 days.
Interaction
Glucocorticoids when combined with carnitine chloride promote its accumulation in tissues (except the liver).
Other anabolic agents increase the effect.
Contraindications
A hypersensitivity to carnitine chloride.
Side effects
Allergic reactions are possible.
Muscular weakness may occur in patients with uremia.
In fast administration (80 drops per minute or more), pain along the veins may occur, which disappears when the rate of administration is reduced.
Pregnancy use
Special studies on the possibility of use during pregnancy and during breastfeeding have not been conducted.
The decision on use should be made by evaluating the ratio of possible risk to the child and benefit to the mother.
Weight | 0.070 kg |
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Shelf life | 4 years. Do not use the drug after the expiration date! |
Conditions of storage | Should be kept out of reach of children and out of the light at a temperature not exceeding 25 ° C. |
Manufacturer | FGBU NRMC of Cardiology, Russia |
Medication form | concentrate for preparation of infusion solution |
Brand | FGBU NRMC of Cardiology |
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