Bupivacaine Grindex Spinal, 5 mg/ml 4 ml 5 pcs

Active ingredient

Composition

How to take, the dosage

The dose depends on the type of anesthesia.

For pain relief in surgery (diagnostic and therapeutic manipulations) 2.5-100 mg are used.

For blockade of the trigeminal nerve – 2.5-12.5 mg; stellate node – 25-50 mg; sacral, brachial plexus – 75-150 mg; intercostal blockade – 10-25 mg; peripheral nerve blockade – 25-150 mg.

For prolonged epidural spinal anesthesia the initial dose is 50 mg, the maintenance dose is 15-25-40 mg every 4-6 hours. For epidural and caudal anesthesia in obstetric practice the dose is 15-50 mg.

Epidural anesthesia for caesarean section is 75-150 mg. For blockade of the pudendal nerve – 12.5-25 mg on each side.

The maximum dose is 2 mg/kg.

Interaction

Concomitant use with antiarrhythmic drugs with local anesthetic activity increases the risk of additive toxic effects.

Concomitant use with barbiturates may decrease the blood concentration of bupivacaine.

Special Instructions

Spinal anesthesia should only be performed under the supervision of an experienced anesthesiologist.

In spinal anesthesia patients with hypovolemia have an increased risk of sudden and severe arterial hypotension.

With caution, use in patients receiving antiarrhythmic drugs with local anesthetic activity.

The dosage form of bupivacaine used must be strictly consistent with the indications for use.

Contraindications

Side effects

CNS and peripheral nervous system: numbness of the tongue, dizziness, blurred vision, muscle tremor, drowsiness, seizures, loss of consciousness. In the area of anesthesia paresthesia and weakening of sphincter tone are possible.

Cardiovascular system disorders: decreased cardiac output, heart block, arterial hypotension, bradycardia, ventricular arrhythmias, cardiac arrest.

Respiratory system: apnea.

Allergic reactions: skin manifestations, in severe cases – anaphylactic shock.

Side effects are rare, the probability of their development increases with the use of an inadequate dose and violation of the technique of bupivacaine administration.