Bupivacaine Grindex Spinal, 5 mg/ml 4 ml 5 pcs

Indications

Spinal anesthesia in surgery (for surgical interventions in urology or lower thoracic surgery lasting up to 3-5 hours; in abdominal surgery – lasting 45-60 minutes).

Pharmacological effect

Amide-type local anesthetic.

Special instructions

Spinal anesthesia should only be performed under the supervision of an experienced anesthesiologist.

During spinal anesthesia, patients with hypovolemia are at increased risk of developing sudden and severe arterial hypotension.

Use with caution in patients receiving antiarrhythmic drugs with local anesthetic activity.

The compliance of the bupivacaine dosage form used with the indications for use should be strictly observed.

Active ingredient

Bupivacaine

Composition

1 ml bupivacaine hydrochloride (monohydrate) 5 mg.

Contraindications

Meningitis, tumors, poliomyelitis, intracranial bleeding, osteochondrosis, spondylitis, tuberculosis, metastatic lesions of the spine, pernicious anemia with neurological symptoms, heart failure in the decompensation phase, massive pleural effusion, significantly increased intra-abdominal pressure, severe ascites, abdominal tumors, severe arterial hypotension (cardiogenic or hypovolemic shock), septicemia, coagulation disorders or anticoagulant therapy, intravenous regional anesthesia according to Bier, paracervical block in obstetrics, in the form of a 0.75% solution for epidural block in obstetrics, pustular skin lesions at the injection site, hypersensitivity to amide-type local anesthetics.

Side Effects

From the central nervous system and peripheral nervous system: numbness of the tongue, dizziness, blurred vision, muscle tremors, drowsiness, convulsions, loss of consciousness. In the area of ​​anesthesia, paresthesia and weakening of sphincter tone are possible.

From the cardiovascular system: decreased cardiac output, heart block, arterial hypotension, bradycardia, ventricular arrhythmias, cardiac arrest.

From the respiratory system: apnea.

Allergic reactions: skin manifestations, in severe cases – anaphylactic shock.

Side effects are rare; the likelihood of their development increases when an inadequate dose is used and the technique of administering bupivacaine is violated.

Interaction

When used simultaneously with antiarrhythmic drugs that have local anesthetic activity, the risk of additive toxic effects increases.

When used simultaneously with barbiturates, the concentration of bupivacaine in the blood may decrease.

Manufacturer

Grindeks JSC, Latvia