Belosalik lotion, 50 ml

Pharmaceutical group:

Glucocorticosteroid+keratolytic agent.

Pharmacological action:

The drug for external use. Belosalik® lotion has anti-inflammatory, antipruritic, antiedematous, anti-allergic, antiproliferative, immunosuppressive, keratolytic, antimicrobial, antifungal effects.

Betamethasone dipropionate is a synthetic GKS that has anti-inflammatory, anti-allergic, antipruritic and vasoconstrictive effects.

When applied to the skin surface it narrows vessels, reduces itching, decreases release of inflammatory mediators (from eosinophils and mast cells), interleukins 1 and 2 and gamma-interferon (from lymphocytes and macrophages), inhibits activity of hyaluronidase and decreases vascular wall permeability.

It interacts with specific receptors in the cell cytoplasm, stimulating the synthesis of mRNA, inducing the formation of proteins, including lipocortin, which mediate cellular effects. Lipocortin inhibits phospholipase A2, blocks the release of arachidonic acid and biosynthesis of endoperoxides, prostaglandins, leukotrienes (contributing to inflammation, allergy and other pathological processes).

Salicylic acid through its keratolytic action cleanses lesion areas of scales, promotes penetration of betamethasone into the skin, maintains an acidic skin environment, preventing the development of bacterial and fungal infection.

Indications

Subacute and chronic dermatoses sensitive to GCS therapy and accompanied by hyperkeratosis and desquamation:

Active ingredient

Composition

1 g of the solution contains:

Active substances:

Betamethasone dipropionate – 640 mcg, which corresponds to the content of betamethasone – 500 mcg;

Salicylic acid – 20 mg.

Auxiliary substances:

dinatrium edetate – 0.3 mg,

hypromellose 4000 cPs – 5 mg,

sodium hydroxide – 5 mg,

isopropanol – 392 mg,

water – 577.06 mg.

How to take, the dosage

The product is for external use.

A few drops of the topical solution are spread evenly over the surface of the skin, rubbing gently. The frequency of use is 2 times a day; in mild cases, a single use is sufficient.

The duration of the continuous course of treatment is usually limited to 3-4 weeks. If a longer course of therapy is necessary, it is recommended that the drug be used less frequently, for example, every other day.

The drug can be prescribed with caution in children from 6 months of age and for the shortest time possible.

Interaction

No clinically significant interactions with other drugs have been noted.

The simultaneous use of cosmetic and dermatological topical products containing ethanol or medical soaps with a strong drying effect may cause skin irritation.

Special Instructions

The drug is for external use only.

Avoid contact with eyes and mucous membranes and use in the anogenital region.

The use of the drug under an occlusive dressing is not recommended unless necessary.

If fungal or bacterial microflora develops on the skin, additional use of an antibacterial or antifungal agent is necessary.

The product Belosalik® lotion in the form of a solution for external use is particularly suitable for use on the scalp. The solution is easy to apply to the surface of the skin, does not stick to or dry out the hair, leaves no visible residue and has a cooling effect on the skin.

Influence on driving and operating ability

There are no reports of adverse effects of Belosalik® Lotion on driving and operating ability.

Contraindications

Side effects

The side effects are usually reversible and mild.

On the skin: hypersensitivity reactions (itching, burning, hyperemia), acne-like changes, hypopigmentation, stretch marks, skin atrophy, hypertrichosis, secondary skin infections may occur.

Long-term continuous uncontrolled use and application to large areas of skin: telangiectasia, systemic side effects of GCS or salicylates.

If hypersensitivity or adverse reactions develop, the drug should be discontinued and a physician consulted.

Overdose

Symptoms: appearance of systemic side effects.

Treatment: Cancellation of the drug and symptomatic therapy is recommended.

Pregnancy use

The use of Belosalik® Lotion in pregnant women is allowed when the expected benefit to the mother outweighs the risk to the fetus. In such cases, the use of the drug should be of short duration and limited to small areas of the skin.

When breastfeeding, Belosalik® Lotion may be used for strict indications, but the drug should not be applied to the breast skin before breastfeeding.

Similarities