Ascorbic acid with glucose, tablets 20 pcs

Ascorbic acid plays an important role in the regulation of redox processes, carbohydrate metabolism, blood coagulation, tissue regeneration, helps to increase the body’s resistance. Ascorbic acid (vitamin C) is not formed in the human body, and comes only with food. With a balanced and nutritious diet, a person does not experience a deficiency of vitamin C.

Indications

Composition

How to take, the dosage

The drug is taken orally, after meals.

In prophylactic purposes it is prescribed:

Adults – ½ – 1 tablet per day.

During pregnancy and lactation, 3 tablets a day for 10-15 days, then 1 tablet a day.

For therapeutic purposes are prescribed:

Adults – ½ to 1 tablet 3-5 times a day.

Children – ½ – 1 tablet 2-3 times a day.

The period of treatment depends on the nature and course of the disease and is recommended by the doctor. .

Interaction

Ascorbic acid increases the blood concentration of benzylpenicillin and tetracyclines; at a dose of 1 g / day increases the bioavailability of ethinylestradiol (including those included in oral contraceptives).

It improves intestinal absorption of iron preparations (converts trivalent iron to divalent iron); it may increase iron excretion if used concomitantly with deferoxamine.

Decreases the effectiveness of heparin and indirect anticoagulants.

Acetylsalicylic acid, oral contraceptives, fresh juices and alkaline drinking reduce absorption and absorption.

Concomitant use with acetylsalicylic acid increases urinary excretion of ascorbic acid and decreases excretion of acetylsalicylic acid. Acetylsalicylic acid reduces the absorption of ascorbic acid by about 30%.

It increases the risk of crystalluria when treated with salicylates and short-acting sulfonamides, slows renal excretion of acids, increases excretion of drugs that have an alkaline reaction (including alkaloids), reduces the blood concentration of oral contraceptives.

Enhances total clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body.

Drugs of the quinoline series, calcium chloride, salicylates, glucocorticosteroids with prolonged use deplete ascorbic acid reserves. When used concomitantly it reduces chronotropic effect of isoprenaline. In long-term use or when used in high doses it can disrupt disulfiram-ethanol interaction.

In high doses increase renal excretion of mexiletine and decrease the therapeutic effects of antipsychotic drugs (neuroleptics) – phenothiazine derivatives, tubal reabsorption of amphetamine and tricyclic antidepressants.

Barbiturates and primidone increase ascorbic acid excretion with urine.

Special Instructions

Due to the stimulating effect of ascorbic acid on the formation of glucocorticosteroid hormones it is necessary to monitor renal function and blood pressure. With long-term use of high doses it is possible suppression of pancreatic insular apparatus function, therefore during treatment it is necessary to monitor regularly the functional ability of the pancreas.

The drug does not affect the ability to drive vehicles, operate precision machinery and engage in other potentially dangerous activities requiring increased concentration and rapid psychomotor reactions.

Contraindications

High sensitivity to the components of the drug, children (under 3 years). Do not prescribe high doses in patients with increased blood clotting, thrombophlebitis and tendency to thrombosis, as well as in patients with diabetes mellitus and conditions accompanied by high blood sugar.

With caution

Overdose

Symptoms: with prolonged use of large doses (more than 1 g) – headache, increased excitability of the central nervous system, insomnia, nausea, vomiting, diarrhea, hyperacid gastritis, ulceration of the mucosa of the gastrointestinal tract, Inhibition of pancreatic insular apparatus function (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis, (from calcium oxalate), damage to the glomerular apparatus of the kidneys, moderate pollakiuria (when taking a dose over 600 mg/day).

Decrease capillary permeability (deterioration of tissue trophism, increased blood pressure, hypercoagulation, development of microangiopathies are possible).

Treatment: in case of ingestion of a potentially toxic dose caused vomiting, in rare cases – gastric lavage, prescribed activated charcoal, laxatives (eg, isotonic solution of sodium sulfate).

Pregnancy use

Ascorbic acid penetrates the placental barrier. It should be borne in mind that the fetus can adapt to high doses of ascorbic acid taken by a pregnant woman, and then the newborn may develop ascorbic acid disease as a withdrawal reaction.

Askorbic acid should therefore not be taken at high doses during pregnancy unless the expected benefit exceeds the potential risk.

Ascorbic acid is excreted with breast milk. A mother’s diet containing adequate amounts of ascorbic acid is sufficient to prevent ascorbic acid deficiency in the infant. It is recommended not to exceed the maximum daily requirement of ascorbic acid by the nursing mother, except in cases where the expected benefit exceeds the potential risk.