Aquadetrim, drops 15000 me/ml 10 ml
€6.22 €5.53
Aquadetrim – Vitamin D3 is a regulator of calcium-phosphorus metabolism. It is an active anti-rachitis factor. The most important function of vitamin D3 is to regulate calcium and phosphate metabolism, which promotes proper mineralization and skeletal growth.
Vitamin D3 is the natural form of vitamin D, which is formed in the human skin by sunlight. Compared with vitamin D2 is characterized by 25% higher activity. Colecalciferol plays an essential role in the absorption of calcium and phosphate from the intestine, in the transport of mineral salts and in the process of calcification of coshes, it also regulates the excretion of calcium and phosphate by the kidneys. The concentration of calcium ions in the blood is responsible for maintaining muscle tone in the skeletal muscles, myocardial function, contributes to nerve excitement, and regulates blood clotting. Vitamin D is necessary for normal function of the parathyroid glands, and is also involved in the functioning of the immune system by influencing the production of lymphokines.
Deficiency of vitamin D in food, impaired absorption, calcium deficiency, as well as lack of exposure to sunlight during intense growth of children leads to rickets and osteomalacia in adults; pregnant women may show symptoms of tetany, disruption of bone calydification processes in newborns. An increased need for vitamin D occurs in women during menopause, as they often develop osteoporosis due to hormonal disorders.
Indications
Prevention and treatment of vitamin D deficiency.
The prevention and treatment of rickets, rickets-like diseases, hypocalcemic tetany, osteomalacia and metabolic bone diseases (such as hypoparathyroidism and pseudohypoparathyroidism).
In the complex treatment of osteoporosis, including postmenopausal.
Active ingredient
Composition
1 ml of the solution (30 drops) contains Colecalciferol (Vitamin D3) – 15 000 ME
Her excipients: macrogoal glycerylicinoleate, sucrose, sodium hydrophosphate dodecahydrate, citric acid monohydrate, anise flavoring (or anise essence), benzyl alcohol, purified water.
How to take, the dosage
Peroral.
Dissolve Aquadetrim in 1 spoonful of liquid.
1 drop contains about 500 ME of vitamin D3.
Unless otherwise prescribed by the doctor, the drug is used in the following dosages:
Preventive doses:
Therapeutic doses:
The dosage is usually prescribed taking into account the amount of vitamin D taken in with food.
Interaction
Antiepileptic agents, rifampicin, cholestyramine decrease reabsorption of vitamin D3.
The simultaneous use with thiazide diuretics increases the risk of hypercalcemia.
Simultaneous use with cardiac glycosides may increase their toxic effects (risk of manifestation of cardiac arrhythmias).
Special Instructions
Avoid overdose.
Individual provision of a specific need should consider all possible sources of this vitamin.
Aquadetrim doses used too high for long periods or shock doses can cause chronic hypervitaminosis D3.
The determination of a child’s daily vitamin D requirement and the route of administration must be established by the doctor individually and adjusted each time during periodic examinations, especially in the first months of life.
Do not use high doses of calcium simultaneously with Aquadetrim.
During treatment, periodic monitoring of calcium and phosphate concentrations in the blood and urine is necessary.
Contraindications
High sensitivity to the components of the drug, especially to benzyl alcohol. Hypervitaminosis D, increased concentration of calcium in blood (hypercalcemia), increased excretion of calcium with urine (hypercalciuria), urolithiasis (formation of calcium oxalate stones), sarcoidosis, acute and chronic liver and kidney diseases, renal failure, active pulmonary tuberculosis. Childhood up to 4 weeks of life.
With caution: immobilization state, while taking thiazides, cardiac glycosides (especially foxglove glycosides); during pregnancy and breastfeeding.
In infants with a predisposition to early congestion of the fontanelle (when from birth small dimensions of the anterior vertex are established).
Side effects
Hypersensitivity to the components of the drug, hypervitaminosis D (symptoms of hypervitaminosis: loss of appetite, nausea, vomiting; headaches, muscle and joint pains; constipation; dry mouth; polyuria; weakness; mental disorders, including depression; weight loss; sleep disturbances; fever; protein, leukocytes, hyaline cylinders appear in urine; blood calcium levels increase and its excretion with urine; calcinosis of kidneys, blood vessels, lungs is possible).
In case of signs of hypervitaminosis D, the drug should be withdrawn, calcium intake should be limited, and vitamins A, C and B should be prescribed.
Overdose
Symptoms: decreased appetite, nausea, vomiting, constipation, restlessness, thirst, polyuria, diarrhea, intestinal colic. Headache, muscle and joint pain, mental disorders including depression, stupor, ataxia, and progressive weight loss are common symptoms. Renal dysfunction develops with albinuria, erythrocyturia and polyuria, increased potassium loss, hypostenuria, nycturia and elevated blood pressure.
In severe cases corneal clouding may occur, less frequently papilloedema of the optic nerve, iris inflammation up to cataract development.
Kidney stones may form, calcification of soft tissues, including blood vessels, heart, lungs and skin.
Rarely, cholestatic jaundice develops.
Treatment:
Discontinue use of Aquadetrim. Contact your doctor. Take plenty of fluids. Hospitalization may be required if necessary.
Pregnancy use
Aquadetrim should not be used in high doses during pregnancy because of the possibility of teratogenic effect in case of overdose.
Aquadetrim should be administered with caution to women breast-feeding a child – the drug taken in high doses by the mother may cause overdose symptoms in the child.
During pregnancy and breast-feeding the dose of vitamin D3 should not exceed 600 ME per day.
Similarities
Weight | 0.044 kg |
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Shelf life | 3 years |
Conditions of storage | In a light-protected place, at a temperature not exceeding 25 °C |
Manufacturer | Polpharma S.A., Poland |
Medication form | oral drops |
Brand | Polpharma S.A. |
Other forms…
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