Albumin, 20% 100 ml

Albumin is a drug for parenteral nutrition.

Maintaining oncotic pressure in the blood, increasing the volume of circulating blood, increasing blood pressure to facilitate the transfer of tissue fluid into the bloodstream, providing the body with proteins.

In clinical practice the indications for the use of albumin solution are almost the same as for plasma, but in many pathological conditions the use of albumin solution has a more rapid and pronounced therapeutic effect.

Indications

Decrease in plasma albumin concentration less than 30 g/l or colloid-oncotic pressure less than 15 mm Hg, or decrease in total protein less than 50 g/l:

Hypoalbuminemia of various genesis – shock (hemorrhagic, traumatic, thermal), acute blood loss (reduction of the BOD by more than 25-30%), purulent-septic conditions, liver diseases with impaired albumin synthesis function, kidney disease (nephritis, nephrotic syndrome), burn disease;

operations with the use of artificial circulation;

therapeutic plasmapheresis;

Hemolytic disease in newborns during exchange blood transfusions;

Preoperative hemodilution and harvesting of autologous blood components;

Brain edema (hyperoncotic solutions);

Gastrointestinal diseases with impaired absorption or permeability.

Active ingredient

Composition

1 ml of the solution contains human albumin 200 mg.

How to take, the dosage

Albumin is administered intravenously by drip or stream.

The single dose depends on the initial condition and age of the patient.

Interaction

The simultaneous use of albumin with ACE inhibitors increases the risk of arterial hypotension.

Contraindications

Arterial hypertension and severe heart failure.

Side effects

In some previously sensitized patients allergic reactions of varying severity may occur.

The complications are extremely rare in persons with a history of intolerance to internal infusions of protein preparations and other plasma substitutes, drugs, serums, vaccines.

Overdose

In case of overdose or too rapid administration of the drug the phenomenon of hypervolemia may occur (development of pulmonary edema, increased arterial and central venous pressure).

In case of initial signs of anaphylactic reaction or signs of overdose (headache, shortness of breath, suffocation) albumin transfusion should be stopped immediately and without removing the needle from the vein the appropriate drugs (glucocorticosteroids, vasopressor drugs if indicated) should be injected.