Abacavir Canon, 300 mg 60 pcs

Antiviral agent, synthetic carbocyclic analogue of nucleosides. Inside the cell abacavir is converted with the participation of cellular enzymes into the active metabolite carbovir triphosphate. Carbovir triphosphate is an analogue of deoxyguanosine-5′-triphosphate (dGTP). Carbovir triphosphate inhibits HIV-1 reverse transcriptase activity due to competition with the natural substrate dGTP and disruption of its incorporation into viral DNA. Loss of the 3′-OH group in the embedded nucleoside analogue prevents the formation of the 5′- and 3′-phosphorus-ether bonds required for DNA strand elongation. As a result, viral DNA growth stops.

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Overdose