🐾 Serenia solution for injection, 20 ml

Serenia belongs to the group of antiemetics.

The active substance of Serenia – maropitant citrate – is an antagonist of neurokinin receptors (NK1) and inhibits the binding of substance P, a tachykinin group neutropeptide in the CNS. Maropitant citrate is effective for vomiting of both central and peripheral genesis. Maropitant is rapidly absorbed from the injection site and reaches maximum plasma concentration 45 minutes after injection. Maropitant is more than 99% bound to plasma proteins.  The bioavailability of Serenia is 90%. Maropitant is metabolized in liver by cytochrome P450, excreted mainly with feces.

By the degree of impact on the body Maropitant citrate refers to moderately hazardous substances (3rd class of hazard according to GOST 12.1.007-76).

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