Trypsin, lyophilizate 10 mg 10 pcs

Trypsin is a proteolytic enzyme obtained from the bovine pancreas. It hydrolyzes proteins and peptones to form relatively low-molecular-weight peptides and cleaves high-molecular-weight products of protein decomposition polypeptides like peptones containing certain amino acids (arginine lysine).

In medical practice the use of trypsin is based on the specific feature of cleaving necrotic tissues and fibrinous formations to liquefy viscous secretions and exudates and with intramuscular administration to have an anti-inflammatory effect.

Indications

Active ingredient

Composition

1 vial contains:

The active ingredient:

trypsin (bovine pancreas) 10 mg.

How to take, the dosage

Intramuscularly. Adults: 5-10 mg 1-2 times a day; children: 2.5 mg once a day. For injections immediately before use 5 mg of trypsin crystalline is diluted in 1-2 ml of 0.9% NaCl solution or 0.5-2% procaine solution. The course of treatment is 6-15 injections. Electrophoresis with trypsin is also used: 10 mg of trypsin (dissolved in 15-20 ml of distilled water) per session, administered from the negative pole.

Inhalation: 5-10 mg in 2-3 ml of 0.9% NaCl solution through an inhaler or through a bronchoscope. After inhalation rinse mouth with warm water and rinse nose.

Eye drops: conjunctival, 0.2-0.25% solution, which is prepared immediately before use.

Intrapleural: once a day, 10-20 mg dissolved in 20-50 ml of 0.9% NaCl solution.

Intrapleural: 50-150 mg in 5-30 ml of phosphate buffered saline, after instillation frequent change of body position is desirable; on day 2 after instillation usually dilute exudate is released.

Topical: Three-layer cloth of dialdehyde cellulose impregnated with trypsin solution is applied to the wound (after treatment) and secured with a dressing, left on the wound for no more than 24 hours. Before application the cloth is moistened with distilled water or furacilin solution. Time of complete cleaning of the wound from necrotic tissues and pus is 24-72 hours. If necessary, reapply.

Interaction

Inhalation alone can add bronchodilators and antibiotics to the solution.

Special Instructions

The drug should not be injected into areas of inflammation and bleeding cavities.

The drug should not be administered intravenously.

Trypsin should not be applied to pitted surfaces of malignant tumors to prevent spread of the malignant process.

Contraindications

Side effects

Pregnancy use

Possible only if the expected benefits to the woman outweigh the possible risks to both the woman and the baby.