Oxamp sodium, 0.5 g

Oxamp sodium is a combined antibacterial drug.

Oxacillin is an antibiotic from the group of semisynthetic penicillins. It acts bactericidally by inhibiting the synthesis of the bacterial cell wall. It is resistant to the action of penicillinase. Active against Gram-positive bacteria: Staphylococcus spp. (including penicillinase-producing), Streptococcus spp. Streptococcus pneumoniae), Corynebacterium diphtheriae, Bacillus anthracis; Gram-negative bacteria: Neisseria gonorrhoeae, Neisseria meningitidis; anaerobic bacteria: spore-forming bacilli, Actinomyces spp. Most gram-negative bacteria, rickettsiae, viruses, protozoa, fungi are resistant to oxacillin.

Ampicillin is an antibiotic of the group of semisynthetic penicillins. It acts bactericidally, inhibiting synthesis of the bacterial cell wall. It is active against Gram-positive bacteria: Staphylococcus spp. (except for penicillinase-producing strains), Streptococcus spp. (including Enterococcus spp.), non-sporulating bacteria (including Listeria monocytogenes); Gram-negative aerobic bacteria: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Shigella spp, Salmonella spp., Bordetella pertussis, some strains of Haemophilus influenzae.

Ampicillin is destroyed by penicillinase.

The combination of ampicillin with oxacillin is rational because the latter, by inhibiting penicillinase activity, reduces the destruction of ampicillin. The spectrum of action with this combination becomes wider.

– burn disease;

– angina.

Prevention of postoperative complications of surgical interventions.

Prevention and treatment of infections in newborns.

Indications

respiratory tract infections (including bronchitis, pneumonia, bronchiectasis);
diseases of the biliary tract (including cholangitis, cholecystitis);
urinary tract and kidney infections (including pyelitis, pyelonephritis, cystitis);
infections of the skin and soft tissues (including infected wounds);
burn disease;
angina.

Prevention of postoperative complications during surgical interventions.

Prevention and treatment of infections in newborns.

Pharmacological effect

Oksamp-sodium is a combined antibacterial drug.

Oxacillin is an antibiotic from the group of semisynthetic penicillins. It has a bactericidal effect, inhibiting the synthesis of bacterial cell walls. Penicillinase resistant. Active against gram-positive bacteria: Staphylococcus spp. (including those producing penicillinase), Streptococcus spp. (including Streptococcus pneumoniae), Corynebacterium diphtheriae, Bacillus anthracis; gram-negative bacteria: Neisseria gonorrhoeae, Neisseria meningitidis; anaerobic bacteria: spore-forming rods, Actinomyces spp. Most gram-negative bacteria, rickettsia, viruses, protozoa, and fungi are resistant to oxacillin.

Ampicillin is an antibiotic from the group of semisynthetic penicillins. It has a bactericidal effect, inhibiting the synthesis of bacterial cell walls. Active against gram-positive bacteria: Staphylococcus spp. (except for penicillinase-producing strains), Streptococcus spp. (including Enterococcus spp.), non-spore-forming bacteria (including Listeria monocytogenes); gram-negative aerobic bacteria: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Shigella spp., Salmonella spp., Bordetella pertussis, some strains of Haemophilus influenzae.

Ampicillin is destroyed by penicillinase.

The combination of ampicillin with oxacillin is rational, because the latter, inhibiting the activity of penicillinase, thereby reduces the destruction of ampicillin. The spectrum of action with this combination becomes wider.

— burn disease;

– angina.

Prevention of postoperative complications during surgical interventions.

Prevention and treatment of infections in newborns.

Special instructions

If allergic reactions occur, it is necessary to stop administering Oxamp-sodium and carry out desensitizing therapy.

Active ingredient

Ampicillin, Oxacillin

Composition

1 bottle of powder contains:

Active substances:

ampicillin sodium 333.33 mg,

oxacillin sodium 166.67 mg

Contraindications

hypersensitivity to the components of the drug and other antibiotics from the penicillin group.

Side Effects

Allergic reactions: skin rash, urticaria, Quincke’s edema; rarely – anaphylactic shock.

Local reactions: with intravenous administration, the development of phlebitis and periphlebitis is possible; with intramuscular injection – pain at the injection site.

Storage conditions

In a place protected from light, at a temperature not exceeding 25 °C.

Manufacturer

Sintez, Russia