Omez, lyophilizate 40 mg
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Gastrointestinal infections caused by Helicobacter pylori, Heartburn, Reflux esophagitis, Peptic ulcer, Pain in the epigastric region, Nausea, Sour belching As an alternative to oral therapy if it is impossible:
- in gastric and duodenal ulcer disease (including prevention of relapse);
- in gastroesophageal reflux disease (GERD);
- with hypersecretory conditions (Zollinger-Ellison syndrome, stress ulcers of the gastrointestinal tract, polyendocrine adenomatosis, systemic mastocytosis);
- for prevention and treatment of gastric and duodenal mucosal damage caused by taking non-steroidal anti-inflammatory drugs (NSAID gastropathy): dyspepsia, mucosal erosions, peptic ulcer;
- to prevent aspiration of acidic stomach contents into the airways during general anesthesia (Mendelsohn syndrome).
How to take, the dosage
Omez® is administered intravenously within 20-30 minutes. It is recommended to administer the solution for infusion immediately after its preparation. Doses are adjusted individually, sometimes a higher dose is required. If the daily dose exceeds 60 mg, the dose should be divided into two doses.
Long-term use of omeprazole at a dose of 20 mg once daily in combination with caffeine, theophylline, piroxicam, diclofenac, naproxen, metoprolol, propranolol, ethanol, cyclosporine, lidocaine, quinidine and estradiol did not lead to changes in their plasma concentrations.
If gastric ulcer is suspected in the early stages, an x-ray or endoscopic examination is necessary to make a correct diagnosis and prescribe adequate treatment.
If there are any worrisome symptoms such as significant spontaneous weight loss, frequent vomiting, dysphagia, vomiting blood or melena, or if there is a peptic ulcer (or suspected peptic ulcer), the possibility of malignancy should be excluded, as treatment with Omez® may alleviate symptoms and delay diagnosis.
Patients at risk of osteoporosis or osteoporotic fractures should be placed under appropriate clinical observation, although a causal relationship of omeprazole/esomeprazole with osteoporotic fractures has not been established.
A decrease in hydrochloric acid secretion leads to increased concentration of chromogranin A (CgA). Increased plasma concentration of CgA may affect the results of examinations to detect neuroendocrine tumors. To prevent this effect, therapy with proton pump inhibitors should be suspended 5 days before CgA concentration testing. If during this time the CgA concentration has not returned to the normal value, the study should be repeated.
During treatment with omeprazole dizziness, drowsiness, visual disturbances may occur, so care should be taken when driving motor transport and performing other potentially dangerous activities that require high concentration and rapid psychomotor reactions.
Hypersensitivity to omeprazole, substituted benzimidazoles or other drug components.
The incidence of adverse drug reactions is stated according to the following grading: very common (>1/10); common (≥1/100, <1/10); infrequent (≥1/1000, <1/100); rare (≥1/10000, <1/1000); very rare (<1/10000, including isolated cases).
Symptoms: confusion, blurred vision, drowsiness, dry mouth, headache, nausea, tachycardia, arrhythmia.
Treatment: symptomatic. Hemodialysis is not sufficiently effective.
Use of the drug during pregnancy is possible only if the estimated benefit to the mother exceeds the potential risk to the fetus.
Omez, Omisak, Gastrozol, Losek MAPS, Ultop, Ortanol, Omitox, Omeprazol, Omeprazol-Teva
|Conditions of storage|
In the light-protected place at a temperature not exceeding 25 ºC.
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