Mizol gel tube, 30 g

Naphtifine is an antifungal agent for external use belonging to the class of allilamines. The mechanism of action is associated with inhibition of squalene-23-epoxidase, which leads to a decrease in the formation of ergosterol which is part of the cell wall of the fungus. It is active against dermatophytes such as Trichophyton epidermophyton and microsporum molds (Aspergillus spp.) yeast fungi (Candida spp. Pityrosporum) and other fungi (such as Sporothrix schenckii).

Against dermatophytes and aspergillus naphthifin acts fungicide. Against yeast fungi the drug has fungicidal or fungistatic activity depending on the strain of the microorganism. It has antibacterial activity against Gram-positive and Gram-negative microorganisms that can cause secondary bacterial infections. It has anti-inflammatory activity that causes rapid disappearance of inflammatory symptoms, especially itching.
Pharmacokinetics:

When applied topically naphthifin quickly penetrates into the skin creating stable antifungal concentrations in its various layers making it possible to use once a day.

Composition

1 ml of the solution contains

Active ingredient: naphthyphine hydrochloride – 10.00 mg

Propylene glycol – 50.00 mg; ethanol (ethyl alcohol) 95% – 400.00 mg; purified water – 475.00 mg.

Directions for use

The gel is applied to clean dry nails and the skin around them (damaged areas) in a thin layer over the entire surface of the nail once a day, after application dry the nail for 1-2 minutes.

The duration of application is from 2 to 8 weeks. If hypersensitivity or an allergic reaction occurs, stop using the gel. Avoid contact with the mucous membranes of the eyes and mouth.

Synopsis

Why choose Evalar antifungal gel “Mizol”?

Like other antifungal agents, “Mizol” contains a 1% solution of naphthyphine, but has a strengthened composition.

As we know, fungal diseases are widespread among people. They are caused by the reproduction of specific fungi in the body, which are most often manifested on the skin of the feet, nails. Infection with fungal diseases can occur from contact with an already sick person.

It is not uncommon to be caused by household items. Most often people visiting baths, manicure rooms, gyms, saunas become ill. Athletes, visitors to outdoor beaches, people who wear heavy shoes for a long time, and people who are distinguished by sweating are at risk. Other causes may be abnormal pH levels of the skin and not thoroughly drying the feet after bathing or exercise and a decrease in immunity.

MISOL gel thanks to its optimally selected composition: – Used as a cosmetic for the care of the nails and skin in case of fungal infections, – Promotes nail and skin regeneration, the disappearance of itching and burning, – Protects against fungus infections.

Contraindications

Hypersensitivity to naphthyphine or propylene glycol.

Pregnancy and breastfeeding (safety and efficacy of use have not been established).

The application of the drug on the wound surface is contraindicated.

With caution:

Childhood (experience with clinical use is limited).

Pregnancy use

The use of the drug Mizol® Evalar during pregnancy and during breastfeeding is contraindicated (safety and efficacy of naphthifin in this category of patients has not been studied).