Hyalurom CS 3 ml syringe, 1 pc
Hyalurom CS is designed to replenish the volume and restore the viscosity of synovial fluid in joints. Hyalurom CS dissolves in the synovial fluid with beneficial effects.
It undergoes local transformations in the joint cavity and normalizes the properties of the synovial fluid, restoring its lubricating and cushioning functions. The highest concentrations of hyaluronic acid in studies were found in synovial fluid and joint capsule, lower concentrations – in synovial membrane, ligaments and
adjacent muscles, excretion is mainly by the kidneys.
A single injection is recommended and the effect lasts for at least 6 months. This therapy for osteoarthritis is generally accepted, safe and effective.
Hyalurome CS when administered once restores the lubricating and cushioning properties of the synovial fluid, has a pronounced and long-term analgesic effect and significantly reduces restriction of joint mobility.
Sodium Hyaluronate is obtained by bacterial fermentation.
– for symptomatic treatment of osteoarthritis of mild, moderate or severe degree;
– for pain and limited mobility caused by degenerative-dystrophic or posttraumatic changes in knee, hip and other synovial joints;
– for pain relief after arthroscopy (use possible not earlier than 1 week after the intervention).
Sodium Hyaluronate, Sodium Chondroitin Sulfate
1 pre-filled syringe of Hyalur CS
Sodium Hyaluronate 60.00 mg
Sodium Chondroitin Sulfate 90.00 mg
Sodium Chloride 10.50 mg
Sodium Dihydrophosphate Monohydrate 1.35 mg
Sodium Dodecahydrate 15.15 mg
Sodium Hydroxide and/or Sodium Chloride Sodium dihydrophosphate monohydrate 1,35 mg
Dinatrium phosphate dodecahydrate 15,15 mg
Sodium hydroxide and/or hydrochloric acid (for pH correction)
Water for injection up to 3,00 ml
How to take, the dosage
Hyalurom CS is intended for intra-articular injection.
The solution should not be injected outside of the joint cavity or in patients with infections or skin conditions in the area of injection.
Intra-articular injection should be administered by specialists trained in intra-articular techniques and performed under aseptic conditions in medical institutions.
The use of local anesthetics before intraarticular injection is possible, such as subcutaneous lidocaine.
The injection site must be properly disinfected (70% alcohol solution or other disinfectants are used). Disinfectants containing quaternary ammonium salts (e.g., benzalkonium chloride) should not be used, since a precipitation reaction is possible.
The fluid should be removed from the joint cavity before the administration of Hyalurom CS.
Arthrocentesis is recommended before the solution is administered.
After removing the protective cap from the syringe tip, attach a sterile needle to the syringe
. Typically a 0.8 x 40mm (21G) needle is used for the knee joint, for other joints we recommend using the appropriate size (17G to 22G) depending on the joint.
The Hyalurome CS is injected into the joint in volume depending on the size of the joint. The joint cavity should not be overloaded.
Each pre-filled syringe is intended for single use. The contents of the syringe must be used immediately after opening. The unused complete solution is not to be stored and must not be re-sterilized.
After injection of Hyaluroma CS, the patient is advised to be gentle and avoid excessive or prolonged stress on the joints (such as running or playing tennis) for 48 hours.
– established hypersensitivity to the components of this medical device;
– presence of active inflammatory or infectious processes in the joint;
– signs of active skin disease or skin infection in the area of the intended injection;
– use in patients diagnosed with autoimmune disease or undergoing immunotherapy;
– use during pregnancy or lactation;
– age under 18 years.
Mild soreness and swelling in the injection area may occur.
The above symptoms are transient and usually disappear after 72 hours.
C.O.Rompharm Company S.R.L., Romania
solution for injection
C.O.Rompharm Company S.R.L.
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