Excedrin, 20 pcs.

Special Instructions

If symptoms persist or worsen after taking this medicine, or if new symptoms occur, you should consult a doctor immediately. When taking the drug in the recommended dose the body receives as much caffeine as one cup of coffee, so you should reduce the consumption of caffeinated products during treatment with this drug to avoid the development of agitation, irritability, insomnia and palpitations due to caffeine overdose.

If overdose is suspected, seek medical assistance immediately, even if there are no symptoms. You should refrain from drinking alcohol while taking the drug due to the increased risk of liver damage and gastrointestinal bleeding. Because acetylsalicylic acid slows blood clotting, the patient undergoing surgery should warn the doctor about taking the drug in advance.

Acetylsalicylic acid in low doses reduces uric acid excretion, and therefore in patients with predisposition the drug may provoke a gout attack. During long-term use of the drug it is necessary to monitor peripheral blood and liver function.

Effect on the ability to drive vehicles and operate mechanisms
No effect of the drug on the ability to drive vehicles and operate mechanisms has been reported.

Synopsis

White film-coated tablets, oblong, with engraved “E” on one side; cross-sectional view – white or almost white core.

Contraindications

Hypersensitivity to any of the components of the drug; gastrointestinal erosive-ulcerative lesions in the acute phase; gastrointestinal bleeding; complete or incomplete combination of bronchial asthma, recurrent nasal and paranasal sinus polyps and intolerance to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (including history of bleeding; hemophilia; hemorrhagic diathesis; hypoprothrombinemia; severe arterial hypertension. in anamnesis); surgical interventions accompanied with bleeding; hemophilia; hemorrhagic diathesis; hypoprothrombinemia; significant arterial hypertension; portal hypertension; severe IBS; glaucoma; avitaminosis K; renal insufficiency; concomitant use of other drugs containing paracetamol, acetylsalicylic acid or other non-steroidal anti-inflammatory drugs; glucose-6-phosphate dehydrogenase deficiency; pregnancy; lactation; hyperexcitability; sleep disorders; children under 15 years (risk of Reye syndrome in children with hyperthermia caused by viral diseases).

Use the drug with caution in gout, liver disease, headaches associated with head trauma, taking anticoagulants, hypoglycemic agents, gout or arthritis, as well as in concurrent use of drugs containing acetylsalicylic acid or other analgesic and antipyretic components.

Side effects

Gastralgia, nausea, vomiting, hepatotoxicity, nephrotoxicity, gastrointestinal erosive lesions, allergic reactions, tachycardia, increased blood pressure, bronchospasm.

With prolonged use – dizziness, headache, vision disorders, tinnitus, decreased platelet aggregation, hypocoagulation, hemorrhagic syndrome (nasal bleeding, bleeding gums, purpura and others).), kidney damage with papillary necrosis, deafness, erythema malignant exudative (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), Reye syndrome in children (hyperpyrexia, metabolic acidosis, nervous system and mental disorders, vomiting, liver function disorders).

Overdose

Symptoms due to the presence of paracetamol (when taken in doses greater than 10-15 g/day): during the first 24 hours pale skin, nausea, vomiting, anorexia, abdominal pain, impaired glucose metabolism, metabolic acidosis. Symptoms of liver function abnormality may appear 12-48 hours after overdose.

Pregnancy use

Although acetylsalicylic acid can be used in the second trimester of pregnancy, the safety of this combination in pregnant and breastfeeding women has not been studied, so the drug is contraindicated in pregnant (all trimesters) and breastfeeding women.

Similarities

Ascophen-P, Coffil-plus, Citramon Ultra, Citramon, Citramon P, Citramon-ExtraCap, Ascophen ULTRA, Brustrio