Diclogen, gel 1%, 50 g

Diclogen is an NSAID, a derivative of phenylacetic acid. Diclogen has a pronounced anti-inflammatory, analgesic and moderate antipyretic effect. The mechanism of action is associated with inhibition of COX activity – the main enzyme of arachidonic acid metabolism, which is a precursor of prostaglandins that play a major role in the pathogenesis of inflammation, pain and fever. Analgesic effect of Diclogen is due to two mechanisms: peripheral (indirectly, through inhibition of prostaglandin synthesis) and central (due to inhibition of prostaglandin synthesis in the central and peripheral nervous system).

Indications

Rheumatoid arthritis, Bursitis, Sciatica, Arthritis, Inflamed tendons, Pain, Back pain, Joint pain (arthralgia), Neuralgia, Pain after injuries and operations, Lumbago, Arthrosis, Periarthritis, Myalgia (muscle pain), Osteoarthritis, Neck pain, Swelling after injuries and operationsJoint syndrome (rheumatoid arthritis, Osteoarthritis, ankylosing spondylitis, gout), degenerative and chronic inflammatory diseases of the musculoskeletal system (osteochondrosis, osteoarthritis, periarthropathy), post-traumatic inflammation of soft tissue and the musculoskeletal system (sprains, bruises). Spine pain, neuralgia, myalgia, arthralgia, pain syndrome and inflammation after operations and injuries, pain syndrome with gout, migraine, algodysmenorrhea, pain syndrome with adnexitis, proctitis, colic (biliary and renal), pain syndrome with infectious and inflammatory diseases of ENT organs.

Active ingredient

Diclofenac

Composition

1 g of gel contains: diclofenac sodium 1 mg

How to take, the dosage

Diclogen is used externally in a dose of 2-4 grams (depending on the area of the painful area) to the affected area 3-4 times a day.

Special Instructions

Avoid getting Diclogen gel in the eyes and on the mucous membranes.

Contraindications

Gastrointestinal erosive and ulcerative lesions in the acute phase, “aspirin triad”, hematopoiesis disorders of unclear etiology, hypersensitivity to diclofenac and components of the used dosage form, or other NSAIDs.

Side effects

Digestive system: nausea, vomiting, anorexia, epigastric pain and discomfort, flatulence, constipation, diarrhea; in some cases – erosive-ulcerative lesions, bleeding and perforations of the gastrointestinal tract; rarely – liver function disorders. In rectal administration in single cases there were cases of inflammation of the large intestine with bleeding, exacerbation of ulcerative colitis.
CNS and peripheral nervous system: dizziness, headache, agitation, insomnia, irritability, fatigue, rarely – paresthesia, visual disturbances (blurred vision, diplopia), tinnitus, sleep disorders, seizures, irritability, tremor, mental disorders, depression.
Blood system: rarely – anemia, leukopenia, thrombocytopenia, agranulocytosis.
Urinary system: rarely – renal dysfunction, edema in predisposed patients.
Dermatological reactions: rarely – hair loss.
Allergic reactions: skin rash, itching; if used in the form of eye drops – itching, redness, photosensitization.

Similarities

Diclac, Diclofenac-Teva, Diclo-F, Orthofen, Diclovit, Voltaren, Voltaren Emulsgel, Diclofenac, Voltaren Patch, Dicloran Plus, Orthofen, Diclofenac-Altfarm, Diclofenac-SOLofarm, Dialrapid