Clarithromycin 500 mg, 10 pcs.

Clarithromycin is an antibiotic of macrolide group that inhibits protein synthesis in a microbial cell by interacting with 50S ribosomal subunit of bacteria. It is active against Streptococcus agalactiae (pyogenes, viridans, pneumoniae), Haemophilus influenzae (parainfluenzae), Neisseria gonorrhoeae, Listeria monocytogenes, Legionella pneumophilia, Mycoplasma pneumoniae, Helicobacter pylori, Campilobacter jejuni, Chlamydia pneumoniae (trachomatis), Moraxella (Branhamella) catarrhalis, Bordetella pertussis, Propionibacterium acnes, Mycobacterium avium, Mycobacterium leprae, Staphylococcus aureus, Ureaplasma urealyticum, Toxoplasma gondii.

When administered orally clarithromycin is metabolized to form the main metabolite 14hydroxyclarithromycin which has the same or 1-2 orders of magnitude less (depending on the type of microorganism) antimicrobial activity than the unchanged substance.

Indications

Infections caused by microorganisms sensitive to clarithromycin – upper respiratory tract infections (laryngitis, pharyngitis, tonsillitis and sinusitis);

lower respiratory tract infections (bronchitis, bacterial pneumonia);

skin and soft tissue infections (folliculitis, furunculosis, impetigo, wound infection);

infections caused by Mycobacterium avium, Chlamydia trachomatis, Helicobacter pylori, Ureaplasma urealyticum.

Pharmacological effect

Clarithromycin, a macrolide antibiotic, inhibits protein synthesis in microbial cells by interacting with the 50S ribosomal subunit of bacteria. Active against Streptococcus agalactiae (pyogenes, viridans, pneumoniae), Haemophilus influenzae (parainfluenzae), Neisseria gonorrhoeae, Listeria monocytogenes, Legionella pneumophilia, Mycoplasma pneumoniae, Helicobacter pylori, Campilobacter jejuni, Chlamydia pneumoniae (trachomatis), Moraxella (Branhamella) catarrhalis, Bordetella pertussis, Propionibacterium acnes, Mycobacterium avium, Mycobacterium leprae, Staphylococcus aureus, Ureaplasma urealyticum, Toxoplasma gondii.

When taken orally, clarithromycin is metabolized to form the main metabolite 14hydroxyclarithromycin, which has the same or 1–2 orders of magnitude less (depending on the type of microorganism) antimicrobial activity than the unchanged substance.

Active ingredient

Clarithromycin

Composition

1 tablet contains 0.5 g clarithromycin

Contraindications

Hypersensitivity to macrolides.

Side Effects

Possible nausea, vomiting, pain in the epigastric region, diarrhea, transient increase in the activity of liver transaminases, skin rash, headache.

Interaction

With the simultaneous administration of clarithromycin with theophylline and carbamazepine, an increase in the content of the latter in the blood plasma was noted.

Overdose

Symptoms: nausea, vomiting, diarrhea.

Treatment: rinse the stomach as quickly as possible, prescribe symptomatic therapy.

Storage conditions

In a place protected from light, at a temperature not exceeding 25 °C.

Manufacturer

Ozon, Russia