Ceftriaxone, 1 g 50 pcs

Ceftriaxone is a third-generation broad-spectrum cephalosporin antibiotic. It acts bactericidally by inhibiting cell membrane synthesis of microorganisms. In vitro suppresses growth of most gram-positive and gram-negative bacteria. Resistant against b-lactamases.

Indications

Sepsis, Vaginal infections, Pyelonephritis, Lung inflammation (pneumonia), Skin infections

Infectious and inflammatory diseases caused by ceftriaxone-sensitive microorganisms, including. Peritonitis, sepsis, meningitis, cholangitis, gallbladder empyema, shigellosis, salmonellosis, pneumonia, lung abscess, pleural empyema, pyelonephritis, infections of bones, joints, skin and soft tissue, genitals, infected wounds and burns.

Prevention of postoperative infection.

Active ingredient

Ceftriaxone

How to take, the dosage

Ceftriaxone is administered v/m or intravenously (by trickle or drip). For adults and children over 12 years of age the average daily dose is 1-2 g ceftriaxone once daily. In severe cases or in cases of infections caused by moderately sensitive pathogens, the daily dose may be increased to 4 g (2 g twice daily).

Interaction

Ceftriaxone and aminoglycosides are synergistic against many Gram-negative bacteria.

Special Instructions

The drug is prescribed with caution to newborns (including prematurely born) due to the high risk of hyperbilirubinemia, ulcerative colitis.

Contraindications

Hypersensitivity to ceftriaxone; pregnancy (I trimester).

Side effects

Allergic reactions: about 1% – urticaria, fever, chills, eosinophilia, rash, itching, exanthema, allergic dermatitis, erythema exudative multiforme, edema, anaphylactic shock. Digestive system: nausea, vomiting, stomatitis, glossitis, diarrhea, pseudomembranous enterocolitis, cholestasis, increased liver transaminases activity, hyperazotemia, hypercreatininemia, increased urea. CNS disorders: headache, dizziness. Blood system: leukopenia, neutropenia, granulocytopenia, thrombocytopenia, hemolytic anemia. Local reactions: when administered intravenously – phlebitis, soreness along the vein, when administered intravenously – soreness at the injection site. Other: superinfection (including candidomycosis, genital mycosis); oliguria, hypocoagulation.

Overdose

Treatment: symptomatic. Hemodialysis and peritoneal dialysis are not effective.