Amikacin, 1000 mg

Amikacin is a semi-synthetic bactericidal antibiotic of aminoglycoside group. It is a III generation aminoglycoside.

Indications

The drug Amikacin is indicated for use in the treatment of infectious and inflammatory diseases caused by gram-negative microorganisms (resistant to gentamicin, sizomycin and kanamycin) or associations of gram-positive and gram-negative microorganisms:
– respiratory tract infections (bronchitis, pneumonia, pleural empyema, lung abscess);
– sepsis;
– septic endocarditis;
– central nervous system infections (including meningitis);
– abdominal infections (including peritonitis);
– urinary tract infections (pyelonephritis, cystitis, urethritis);
– purulent infections of the skin and soft tissues (including infected burns, infected ulcers and bedsores of various origins);
– biliary tract infections;
– infections of bones and joints (including osteomyelitis);
– wound infection;
– postoperative infections.

Pharmacological effect

Amikacin is a semisynthetic bactericidal antibiotic of the aminoglycoside group. It is a third generation aminoglycoside.

Active ingredient

Amikacin

Composition

1 ml – 1 ampoule of the drug Amikacin contains: amikacin (in the form of sulfate).

Contraindications

Contraindications to the use of the drug Amikacin are: neuritis of the auditory nerve; severe chronic renal failure with azotemia and uremia; pregnancy; hypersensitivity to the components of the drug; history of hypersensitivity to other aminoglycosides.

Side Effects

From the digestive system: nausea, vomiting, liver dysfunction (increased activity of liver transaminases, hyperbilirubinemia).

Interaction

Amikacin exhibits synergism when interacting with carbenicillin, benzylpenicillin, and cephalosporins (in patients with severe chronic renal failure, when used together with beta-lactam antibiotics, the effectiveness of aminoglycosides may be reduced).

Overdose

Symptoms of an overdose of Amikacin: toxic reactions – hearing loss, ataxia, dizziness, urination disorders, thirst, loss of appetite, nausea, vomiting, ringing or a feeling of congestion in the ears, breathing problems.

Storage conditions

List B. The drug Amikacin should be stored out of the reach of children, in a dry place, protected from light at a temperature of 5° to 25°C.

Shelf life

2 years

Manufacturer

Sintez, Russia