Ambroxol, syrup 15 mg/5 ml 100 ml

Tracheitis, Respiratory tract infections, Lung inflammation (pneumonia), Bronchitis, Chronic obstructive pulmonary disease, Bronchial asthma, Cough

Respiratory diseases with formation of viscous sputum: acute and chronic bronchitis, pneumonia, COPD, asthma with sputum retention, bronchiectatic disease.

Stimulation of prenatal lung maturation and treatment and prevention (at risk of preterm birth and at indicated artificial preterm birth between 28 and 34 weeks of pregnancy, if the clinical picture suggests prolongation of pregnancy by 3 days) of respiratory distress syndrome in premature infants and newborns.

Active ingredient

Ambroxol

How to take, the dosage

Syrup (3 mg/ml) for adults – in the first 2-3 days 10 ml and then 5 ml 3 times a day or 10 ml 2 times a day. In severe cases the dose is not reduced during the entire course of treatment. Children of 5-12 years of age are prescribed 15 mg 2-3 times a day, 2-5 years of age – 7.5 mg 3 times a day, up to 2 years of age – 7.5 mg 2 times a day.

Interaction

Co-use with anti-cough drugs leads to difficulty of expectoration of sputum on the background of reduction of coughing.

The penetration of amoxicillin, cefuroxime, erythromycin and doxycycline into the bronchial secretion is increased.

The solution for injection should not be used with solutions having pH higher than 6.3.

Special Instructions

Do not combine with anti-cough medications that make it difficult to expectorate sputum.

The inhalation solution can be used with any modern inhalation equipment (except steam inhalers). Before inhalation the preparation is mixed with 0.9% NaCl solution (for optimal air humidification it can be diluted in 1:1 ratio) and heated to body temperature. Inhalations should be performed in normal breathing mode (so as not to provoke coughing tremors).

Patients with bronchial asthma, in order to avoid non-specific irritation of the airways and their spasm, bronchodilators should be used before inhaling ambroxol.
Patients with diabetes can be prescribed as a syrup (5 ml syrup contains sorbitol and saccharin in an amount corresponding to 0.18 CFU).

Children under 5 years of age are not recommended to use suppositories 15 mg, under 12 years – 30 mg (for them use suppositories 15 mg).

Contraindications

Hypersensitivity, pregnancy (I trimester), phenylketonuria (for dosage forms containing aspartame).
With caution. Liver failure, renal failure, peptic ulcer, pregnancy (II-III trimester), lactation.

Side effects

Allergic reactions: skin rash, urticaria, angioneurotic edema, in some cases – allergic contact dermatitis, anaphylactic shock.

Rarely, weakness, headache, diarrhea, dryness of the mucous membrane of the mouth and respiratory tract, exanthema, rhinorrhea, constipation, dysuria. With long-term use in high doses – gastralgia, nausea, vomiting.

In case of rapid IV administration – feeling of stupor, adynamia, intense headaches, decreased BP, shortness of breath, hyperthermia, chills.

Overdose

Symptoms: nausea, vomiting, diarrhea, dyspepsia.

Treatment: artificial vomiting, gastric lavage in the first 1-2 hours after taking the drug; intake of fat-containing products.

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Pregnancy use

Use during pregnancy (first trimester) is contraindicated.

Similarities

Ambrohexal, Lazolvan, Halixol, Ambroxol, Ambrobene, Orvis Broncho, ORVIS, Lazolvan Max, Zvezdochka, Zvezdochka for colds