Aciclovir Belupo, cream 5% 5 g

Acyclovir is active against Herpes simplex types 1 and 2, Varicella zoster virus, Epstein Barr virus and cytomegaloviruses. Thymidine kinase of virus-infected cells converts acyclovir into acyclovir mono-, di- and triphosphate through a series of activation reactions.

Indications

Infections of the skin and mucous membranes caused by the Herpes simplex virus types 1 and 2, genital herpes, herpes zoster, chickenpox.

Pharmacological effect

Acyclovir is active against Herpes simplex types 1 and 2, Varicella zoster virus, Epstein Barr virus and cytomegaloviruses. Thymidine kinase of virus-infected cells, through a series of sequential activio reactions, converts acyclovir into mono-, di- and triphosphate of acyclovir.

Special instructions

To achieve the maximum therapeutic effect, it is necessary to start using the drug as soon as possible after the onset of infection (at the first signs of the disease: burning, itching, tingling, feeling of tension and redness).

The cream is not recommended to be applied to the mucous membranes of the mouth and eyes, as severe local inflammation may develop. When treating genital herpes, you should avoid sexual intercourse or use condoms, since the use of acyclovir does not prevent transmission of the virus to partners.

Active ingredient

Acyclovir

Composition

Active substance – acyclovir 5 g

Pregnancy

Adequate and controlled clinical studies of the safety of the drug during pregnancy have not been conducted. Use is indicated only in cases where the expected benefit to the mother outweighs the potential risk to the fetus.

During the treatment period, it is necessary to decide on stopping breastfeeding.

Contraindications

Hypersensitivity to acyclovir and other components of the drug.
With caution – pregnancy, lactation, dehydration, renal failure.

Side Effects

Hyperemia, dryness, peeling of the skin; burning, inflammation upon contact with mucous membranes. Allergic dermatitis may develop.

Interaction

When used externally, no interactions with other drugs were detected.

Storage conditions

List B. At temperatures from 12 to 15°C. Keep out of the reach of children.

Shelf life

2 years

Manufacturer

Belupo, medicines and cosmetics d.d., Croatia